Dipyridyl

Dipyridyl

SCHEMBL1927728

[Ru].[Ru].[Ru].c1ccc(-c2ccccn2)nc1

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.93
LMNA P02545 3/20 0.93
CCR1 P32246 3/20 0.93
CCR5 P51681 3/20 0.93
CCR8 P51685 3/20 0.93
CYP1A2 P05177 1/20 0.93
POLB P06746 1/20 0.93
METAP1 P53582 1/20 0.93
BLM P54132 1/20 0.93
HIF1A Q16665 1/20 0.93
DOHH Q9BU89 1/20 0.93
P4HTM Q9NXG6 1/20 0.93
NPC1 O15118 6/20 0.74
TP53 P04637 4/20 0.74
RAB9A P51151 4/20 0.74
ALOX15 P16050 3/20 0.74
SMN1; SMN2 Q16637 3/20 0.74
L3MBTL1 Q9Y468 3/20 0.74
HTT P42858 2/20 0.74
TDP1 Q9NUW8 2/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dipyridyl SCHEMBL5145001 1.00 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL27882761 1.00 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL498331 1.00 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL137577 1.00 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL310586 1.00 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL2245805 0.97 KDM4E (0.88) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL6037873 0.97 KDM4E (0.88) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL8765640 0.97 KDM4E (0.88) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL7619601 0.97 KDM4E (0.88) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL30984375 0.97 KDM4E (0.88) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0628805-B1 Luminescent optical indicator for measuring the activity of alkali metal ions in a sample solution AVL MEDICAL INSTR AG (CH) 1996-09-18 EP claimed
US-5464587-A In blood AVL MEDICAL INSTRUMENTS AG (CH) 1995-11-07 US claimed
EP-0628805-A1 Luminescent optical indicator for measuring the activity of alkali metal ions in a sample solution AVL Medical Instruments AG (CH) 1994-12-14 EP claimed
CN-114062460-A Preparation method of ultralow-potential electrochemiluminescence gold nanocluster and construction of luminescent system thereof 山东大学 2022-02-18 CN disclosed
US-8536333-B2 Neutral metallic dendrimer complexes ISIS INNOVATION LIMITED (GB) 2013-09-17 US disclosed
US-20110127496-A1 Neutral Metallic Dendrimer Complexes CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2011-06-02 US disclosed
US-7799917-B2 Neutral metallic dendrimer complexes ISIS INNOVATION LIMTED (GB) 2010-09-21 US disclosed
EP-1532158-B1 NEUTRAL METALLIC DENDRIMER COMPLEXES ISIS INNOVATION (GB) 2008-10-15 EP disclosed
US-20060119254-A1 Neutral metallic dendrimer complexes CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2006-06-08 US disclosed
EP-1532158-A1 NEUTRAL METALLIC DENDRIMER COMPLEXES ISIS INNOVATION LIMITED (GB) 2005-05-25 EP disclosed
WO-2004020448-A1 NEUTRAL METALLIC DENDRIMER COMPLEXES ISIS INNOVATION LIMITED (GB) 2004-03-11 WO disclosed
US-6525200-B1 Fused pyridine and cyclohexane rings and having optionally other substituents; complexing and quantitating such as urea or guanidine ROCHE DIAGNOSTICS CORPORATION 2003-02-25 US disclosed
WO-2002014465-A2 MULTICYCLIC AROMATIC COMPOUNDS AND USES THEREOF ROCHE DIAGNOSTICS CORPORATION (US) 2002-02-21 WO disclosed
US-5541113-A Method for detecting an analyte using an electrochemical luminescent transition metal label BECKMAN INSTRUMENTS, INC. (US) 1996-07-30 US disclosed
US-5541113-A Method for detecting an analyte using an electrochemical luminescent transition metal label BECKMAN INSTRUMENTS, INC. (US) 1996-07-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060119254-A1 Neutral metallic dendrimer complexes ZYX, MLX, ZFX KDM4E 3503/4885LMNA 1636/4885CCR1 751/4885
US-20110127496-A1 Neutral Metallic Dendrimer Complexes ZYX, MLX, ZFX KDM4E 3503/4885LMNA 1636/4885CCR1 751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.