Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Dipyridyl. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 known ✓ | P51681 | 3/20 | 0.88 |
| ▸ | HSP90AA1 known ✓ | P07900 | 1/20 | 0.70 |
| ▸ | GLA known ✓ | P06280 | 1/20 | 0.59 |
| ▸ | CYP19A1 known ✓ | P11511 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.88 |
| ▸ | LMNA | P02545 | 3/20 | 0.88 |
| ▸ | CCR1 | P32246 | 3/20 | 0.88 |
| ▸ | CCR8 | P51685 | 3/20 | 0.88 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.88 |
| ▸ | POLB | P06746 | 1/20 | 0.88 |
| ▸ | METAP1 | P53582 | 1/20 | 0.88 |
| ▸ | BLM | P54132 | 1/20 | 0.88 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.88 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.88 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.88 |
| ▸ | NPC1 | O15118 | 6/20 | 0.70 |
| ▸ | TP53 | P04637 | 4/20 | 0.70 |
| ▸ | RAB9A | P51151 | 4/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipyridyl SCHEMBL5251632 | 1.00 | KDM4E (0.88) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL5663541 | 1.00 | KDM4E (0.88) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL646317 | 1.00 | KDM4E (0.88) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL7619601 | 1.00 | KDM4E (0.88) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL8214175 | 0.97 | KDM4E (0.82) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL5555235 | 0.97 | KDM4E (0.82) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL6517724 | 0.97 | KDM4E (0.82) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL608684 | 0.97 | KDM4E (0.82) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL6496504 | 0.97 | KDM4E (0.82) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL6304360 | 0.97 | KDM4E (0.82) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215883-A1 | PHOTOCROSSLINKABLE SYNTHETIC POLYMERS | COOK BIOTECH INCORPORATED (US) | 2023-11-09 | — | — | WO | claimed |
| US-20250345478-A1 | PHOTOCROSSLINKABLE SYNTHETIC POLYMERS | Cook Biotech Incoporated (US) | 2025-11-13 | — | — | US | disclosed |
| US-20250325727-A1 | PHOTOCURABLE ADHESIVES WITH FERULATED PECTIN | COOK BIOTECH INCORPORATED (US) | 2025-10-23 | — | — | US | disclosed |
| WO-2023215883-A1 | PHOTOCROSSLINKABLE SYNTHETIC POLYMERS | COOK BIOTECH INCORPORATED (US) | 2023-11-09 | — | — | WO | disclosed |
| US-20160114075-A1 | PHOTOACTIVATED CROSSLINKING OF A PROTEIN OR PEPTIDE | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2016-04-28 | — | — | US | disclosed |
| US-9216235-B2 | Photoactivated crosslinking of a protein or peptide | COOK MEDICAL TECHNOLOGIES LLC (US) | 2015-12-22 | — | — | US | disclosed |
| CN-102504802-A | Metallic organic luminescent molecule and hydrotalcite compounded electrochemiluminiscent ultrathin film and method of preparing same | UNIV BEIJING CHEMICAL | 2012-06-20 | — | — | CN | disclosed |
| US-20110190813-A1 | PHOTOACTIVATED CROSSLINKING OF A PROTEIN OR PEPTIDE | ELVIN, Christopher M. (AU) | 2011-08-04 | — | — | US | disclosed |
| EP-2178949-A1 | PHOTOACTIVATED CROSSLINKING OF A PROTEIN OR PEPTIDE | Commonwealth Scientific and Industrial Research Organisation (AU) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009021287-A1 | PHOTOACTIVATED CROSSLINKING OF A PROTEIN OR PEPTIDE | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2009-02-19 | — | — | WO | disclosed |
| US-6297018-B1 | LOCATING SAMPLE AT EXAMINATION SITE, ILLUMINATING WITH POLARIZED LIGHT, DETECTING LIGHT EMITTED ONLY FROM VOLUME LOCATED AWAY FROM SAMPLE BOUNDARY INTERFACES, THEN ANALYZING DATA | LJL BIOSYSTEMS, INC. | 2001-10-02 | — | — | US | disclosed |
| WO-2000055372-A1 | METHODS AND APPARATUS FOR DETECTING NUCLEIC ACID POLYMORPHISMS | LJL BIOSYSTEMS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |
| WO-1999037203-A9 | APPARATUS AND METHODS FOR IMPROVING SIGNAL RESOLUTION IN OPTICAL SPECTROSCOPY | LJL BIOSYSTEMS INC (US) | 1999-11-18 | — | — | WO | disclosed |
| WO-1999037203-A2 | APPARATUS AND METHODS FOR IMPROVING SIGNAL RESOLUTION IN OPTICAL SPECTROSCOPY | LJL BIOSYSTEMS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |
| US-5292409-A | Electrolytically generating superoxide ion under protective layer of ion exchange material | CAPE COD RESEARCH, INC. (US) | 1994-03-08 | — | — | US | disclosed |
| US-4977320-A | Electrospray ionization mass spectrometer with new features | THE ROCKEFELLER UNIVERSITY (US) | 1990-12-11 | — | — | US | disclosed |
| EP-0043251-B1 | CATALYST FOR THE PHOTODECOMPOSITION OF WATER, AND A PROCESS FOR THE PREPARATION THEREOF | SIBIT S.p.A. (IT) | 1984-10-03 | — | — | EP | disclosed |
| US-4370263-A | Catalyst for the photo-decomposition of water and process for the preparation of the catalyst | SIBIT, S.P.A. (IT) | 1983-01-25 | — | — | US | disclosed |
| EP-0043251-A2 | Catalyst for the photodecomposition of water, and a process for the preparation thereof | SIBIT S.p.A. (IT) | 1982-01-06 | — | — | EP | disclosed |
| US-3964912-A | Ruthenium containing photographic developers | EASTMAN KODAK COMPANY (US) | 1976-06-22 | — | — | US | disclosed |