SCHEMBL1927732

SCHEMBL1927732

O=C(O)c1ccc(C=Cc2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 2/20 0.67
ALDH1A1 P00352 2/20 0.60
TSHR P16473 2/20 0.59
DAO P14920 1/20 0.59
NAPRT Q6XQN6 1/20 0.59
SRD5A2 P31213 2/20 0.59
SRD5A1 P18405 1/20 0.59
TTR P02766 2/20 0.58
TP53 P04637 1/20 0.57
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
FBP1 P09467 1/20 0.57
CES2 O00748 1/20 0.56
CES1 P23141 1/20 0.56
KMT2A Q03164 2/20 0.56
PTPN1 P18031 1/20 0.55
HNF4A P41235 1/20 0.55
NPC1 O15118 1/20 0.54
GAA P10253 1/20 0.54
MAPK1 P28482 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8437189 1.00 HDAC1 (0.67) HDAC1ALDH1A1TSHRDAONAPRT
SCHEMBL11545296 1.00 HDAC1 (0.67) HDAC1ALDH1A1TSHRDAONAPRT
SCHEMBL1927729 1.00 HDAC1 (0.67) HDAC1ALDH1A1TSHRDAONAPRT
Hydrochloric Acid SCHEMBL4353116 0.98 HDAC1 (0.64) HDAC1ALDH1A1TSHRDAONAPRT
SCHEMBL4364948 0.94 HDAC1 (0.60) HDAC1ALDH1A1TSHRDAONAPRT
Cyanide SCHEMBL11191586 0.94 HDAC1 (0.60) HDAC1ALDH1A1TSHRDAONAPRT
(Z)-1,2-Diphenylethene SCHEMBL18050254 0.93 TSHR (0.70) HDAC1ALDH1A1TSHRDAONAPRT
(Z)-1,2-Diphenylethene SCHEMBL29118837 0.93 TSHR (0.70) HDAC1ALDH1A1TSHRDAONAPRT
SCHEMBL9681086 0.93 ALDH1A1 (0.68) HDAC1ALDH1A1TSHRDAONAPRT
SCHEMBL69167 0.93 ALDH1A1 (0.68) HDAC1ALDH1A1TSHRDAONAPRT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4978735-A Thermotropic liquid crystalline aromatic polyester from 3,3'-diphenyl-4,4'-d HIMONT ITALIA S.R.L. (IT) 1990-12-18 US claimed
EP-0358147-A2 Thermotropic liquid crystalline aromatic polyesters HIMONT ITALIA S.r.l. (IT) 1990-03-14 EP claimed
EP-4636041-A1 COMPOSITE POLYMER MATERIAL, METHOD FOR PRODUCING SAME, AND OPTICAL MATERIAL The University of Osaka (JP) 2025-10-22 EP disclosed
US-20240327578-A1 SILICONE-BASED POLYMER COMPOUND AND SILICONE-BASED POLYMER MATERIAL OSAKA UNIVERSITY (JP) 2024-10-03 US disclosed
US-12054571-B2 Host-group-containing polymerizable monomer, polymer material, method for producing same, and clathrate compound and method for producing same OSAKA UNIVERSITY (JP) 2024-08-06 US disclosed
WO-2024128306-A1 COMPOSITE POLYMER MATERIAL, METHOD FOR PRODUCING SAME, AND OPTICAL MATERIAL 国立大学法人大阪大学 2024-06-20 WO disclosed
EP-4375312-A1 SILICONE-BASED POLYMER COMPOUND AND SILICONE-BASED POLYMER MATERIAL OSAKA UNIVERSITY (JP) 2024-05-29 EP disclosed
CN-117693545-A Organosilicon polymer compound and organosilicon polymer material 国立大学法人大阪大学 2024-03-12 CN disclosed
CN-113816903-B Tetrahydroisoquinoline stilbene compound and preparation method and application thereof 蚌埠医学院 2023-11-14 CN disclosed
US-20230192931-A1 HOST-GROUP-CONTAINING POLYMERIZABLE MONOMER, POLYMER MATERIAL, METHOD FOR PRODUCING SAME, AND CLATHRATE COMPOUND AND METHOD FOR PRODUCING SAME OSAKA UNIVERSITY (JP) 2023-06-22 US disclosed
CN-111801355-B Polymer material and method for producing same 国立大学法人大阪大学 2023-02-28 CN disclosed
EP-0570932-A2 Styrenic block copolymer and process for producing same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-11-24 EP disclosed
US-5231223-A PROCESS FOR THE ARYLATION OF OLEFINS BAYER AKTIENGESELLSCHAFT (DE) 1993-07-27 US disclosed
EP-0475238-A2 Mesogenic glycidyl esters THE DOW CHEMICAL COMPANY (US) 1992-03-18 EP disclosed
EP-0472525-A1 PROCESS FOR THE PREPARATION OF STILBENE DERIVATIVES EASTMAN KODAK COMPANY (US) 1992-03-04 EP disclosed
EP-0391204-A2 Process for preparing moulded articles of polymers with E-configurated stilbene moieties BAYER AG (DE) 1990-10-10 EP disclosed
WO-1990010001-A1 PROCESS FOR THE PREPARATION OF STILBENE DERIVATIVES EASTMAN KODAK COMPANY (US) 1990-09-07 WO disclosed
US-4918215-A 4-halogenostilbene derivatives and processes for their preparation CIBA-GEIGY CORPORATION (US) 1990-04-17 US disclosed
US-4723028-A DIAGNOSIS OF LEUKEMIA SHUDO KOICHI (JP) 1988-02-02 US disclosed
US-4219477-A Penicillin derivatives NIPPON CHEMIPHAR COMPANY LIMITED (JP) 1980-08-26 US disclosed