Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19277945 | 0.81 | — | — | |
| SCHEMBL3396592 | 0.80 | CHRM3 (0.45) | HDAC4HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL3397960 | 0.79 | CHRM3 (0.44) | HDAC4HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL7776196 | 0.73 | — | — | |
| SCHEMBL7776198 | 0.73 | — | — | |
| SCHEMBL758157 | 0.72 | FAAH (0.31) | — | |
| SCHEMBL581196 | 0.72 | — | — | |
| SCHEMBL7771926 | 0.71 | FAAH (0.31) | — | |
| SCHEMBL720598 | 0.70 | — | — | |
| SCHEMBL310711 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3416937-B1 | PROCESS FOR PREPARING SPIROGALBANONE | GIVAUDAN SA (CH) | 2020-10-21 | — | — | EP | disclosed |
| US-10227280-B1 | Process for preparing spirogalbanone | Givaudan, S.A. (CH) | 2019-03-12 | — | — | US | disclosed |
| US-20190055181-A1 | Process For Preparing Spirogalbanone | GIVAUDAN SA (CH) | 2019-02-21 | — | — | US | disclosed |
| WO-2017140607-A1 | PROCESS FOR PREPARING SPIROGALBANONE | GIVAUDAN SA (CH) | 2017-08-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10227280-B1 | Process for preparing spirogalbanone | ADH1C, GALE, AKR1C3 | HDAC4 1475/4885HDAC2 1021/4885HDAC8 1764/4885 |
| US-20190055181-A1 | Process For Preparing Spirogalbanone | ADH1C, GALE, AKR1C3 | HDAC4 1471/4885HDAC2 1015/4885HDAC8 1718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.