SCHEMBL19278950

SCHEMBL19278950

O=C(NCCSSCCNc1c(F)c(F)c(-c2c3nc(c(-c4cccc(O)c4)c4ccc([nH]4)c(-c4cccc(O)c4)c4nc(c(-c5cccc(O)c5)c5ccc2[nH]5)C=C4)C=C3)c(F)c1F)OC[C@H]1[C@@H]2CCC#CCC[C@@H]21

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CYCS P99999 1/20 0.32
▸ ESR1 P03372 1/20 0.32
▸ ESR2 Q92731 1/20 0.32
▸ DHODH Q02127 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19278977 1.00 CYCS (0.32) CYCSESR1ESR2DHODH
SCHEMBL31310036 1.00 CYCS (0.32) CYCSESR1ESR2DHODH
SCHEMBL19289768 0.93 ESR1 (0.32) CYCSESR1ESR2DHODH
SCHEMBL19289594 0.93 ESR1 (0.32) CYCSESR1ESR2DHODH
SCHEMBL19278953 0.92 ESR1 (0.34) CYCSESR1ESR2DHODH
SCHEMBL31310041 0.92 ESR1 (0.34) CYCSESR1ESR2DHODH
SCHEMBL19278954 0.92 ESR1 (0.34) CYCSESR1ESR2DHODH
SCHEMBL22301052 0.90 CYCS (0.32) CYCSESR1ESR2
SCHEMBL22301053 0.90 CYCS (0.32) CYCSESR1ESR2
SCHEMBL19296890 0.86 CYCS (0.31) CYCSESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3210626-B1 CONJUGATES OF PORPHYRINOID PHOTOSENSITIZERS AND GLYCEROL-BASED POLYMERS FOR PHOTODYNAMIC THERAPY BIOLITEC HOLDING GMBH & CO KG (AT) 2024-11-27 — — EP disclosed
US-10738059-B2 Conjugates of porphyrinoid photosensitizers and glycerol-based polymers for photodynamic therapy BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) 2020-08-11 — — US disclosed
US-10738059-B2 Conjugates of porphyrinoid photosensitizers and glycerol-based polymers for photodynamic therapy BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) 2020-08-11 — — US disclosed
US-20170247384-A1 CONJUGATES OF PORPHYRINOID PHOTOSENSITIZERS AND GLYCEROL-BASED POLYMERS FOR PHOTODYNAMIC THERAPY BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) 2017-08-31 — — US disclosed
US-20170247384-A1 CONJUGATES OF PORPHYRINOID PHOTOSENSITIZERS AND GLYCEROL-BASED POLYMERS FOR PHOTODYNAMIC THERAPY BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) 2017-08-31 — — US disclosed
US-20170247384-A1 CONJUGATES OF PORPHYRINOID PHOTOSENSITIZERS AND GLYCEROL-BASED POLYMERS FOR PHOTODYNAMIC THERAPY BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) 2017-08-31 — — US disclosed
EP-3210626-A1 CONJUGATES OF PORPHYRINOID PHOTOSENSITIZERS AND GLYCEROL-BASED POLYMERS FOR PHOTODYNAMIC THERAPY biolitec Unternehmensbeteiligungs II AG (AT) 2017-08-30 — — EP disclosed
EP-3210626-A1 CONJUGATES OF PORPHYRINOID PHOTOSENSITIZERS AND GLYCEROL-BASED POLYMERS FOR PHOTODYNAMIC THERAPY biolitec Unternehmensbeteiligungs II AG (AT) 2017-08-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10738059-B2 Conjugates of porphyrinoid photosensitizers and glycerol-based polymers for photodynamic therapy FPGS, PPOX, UROD CYCS 2671/4885ESR1 2080/4885ESR2 4013/4885
US-20170247384-A1 CONJUGATES OF PORPHYRINOID PHOTOSENSITIZERS AND GLYCEROL-BASED POLYMERS FOR PHOTODYNAMIC THERAPY FPGS, PPOX, UROD CYCS 2671/4885ESR1 2080/4885ESR2 4013/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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