SCHEMBL19278971

SCHEMBL19278971

NCCCCCCNc1c(F)c(F)c(F)c(F)c1C1=C2C=CC(=N2)C(c2cccc(O)c2)=C2C=CC(=N2)C(c2cccc(O)c2)=C2C=CC(=N2)C(c2cccc(O)c2)=C2C=CC1=N2

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ HSP90AA1 P07900 1/20 0.35
▸ HSP90AB1 P08238 1/20 0.35
▸ CHRNA1 P02708 2/20 0.32
▸ CHRNG P07510 2/20 0.32
▸ CHRNB1 P11230 2/20 0.32
▸ CHRND Q07001 2/20 0.32
▸ HPGDS O60760 1/20 0.31
▸ NPY1R P25929 1/20 0.30
▸ NPY5R Q15761 1/20 0.30
▸ SSTR2 P30874 1/20 0.30
▸ SSTR4 P31391 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19278961 0.82 — —
SCHEMBL19278959 0.81 — —
SCHEMBL17651814 0.81 HSD17B1 (0.38) —
SCHEMBL17651780 0.81 HSD17B1 (0.38) —
SCHEMBL19278973 0.76 LCK (0.30) —
SCHEMBL19278970 0.73 HSP90AA1 (0.36) HSP90AA1HSP90AB1
SCHEMBL249200 0.73 HSD17B1 (0.47) —
SCHEMBL17651802 0.73 PIK3CG (0.30) —
SCHEMBL19837814 0.73 PIK3CG (0.30) —
SCHEMBL19278955 0.72 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10738059-B2 Conjugates of porphyrinoid photosensitizers and glycerol-based polymers for photodynamic therapy BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) 2020-08-11 — — US disclosed
US-20170247384-A1 CONJUGATES OF PORPHYRINOID PHOTOSENSITIZERS AND GLYCEROL-BASED POLYMERS FOR PHOTODYNAMIC THERAPY BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) 2017-08-31 — — US disclosed
EP-3210626-A1 CONJUGATES OF PORPHYRINOID PHOTOSENSITIZERS AND GLYCEROL-BASED POLYMERS FOR PHOTODYNAMIC THERAPY biolitec Unternehmensbeteiligungs II AG (AT) 2017-08-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10738059-B2 Conjugates of porphyrinoid photosensitizers and glycerol-based polymers for photodynamic therapy FPGS, PPOX, UROD HSP90AA1 892/4885HSP90AB1 1428/4885CHRNA1 4876/4885
US-20170247384-A1 CONJUGATES OF PORPHYRINOID PHOTOSENSITIZERS AND GLYCEROL-BASED POLYMERS FOR PHOTODYNAMIC THERAPY FPGS, PPOX, UROD HSP90AA1 892/4885HSP90AB1 1428/4885CHRNA1 4876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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