SCHEMBL1928067

SCHEMBL1928067

C=C[Si](C)(C=C)O[Si](O[Si](C)(C)C)(c1ccccc1)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15878857 0.94 ESR1 (0.33) ESR1ESR2
SCHEMBL2600710 0.87
SCHEMBL15779876 0.85 ESR1 (0.31) ESR1ESR2
SCHEMBL94228 0.84 ESR1 (0.39) ESR1ESR2
SCHEMBL16521498 0.82 ESR1 (0.38) ESR1ESR2
SCHEMBL8992173 0.82 ESR1 (0.38) ESR1ESR2
SCHEMBL15830979 0.82
SCHEMBL4867196 0.81 ESR1 (0.31) ESR1ESR2
SCHEMBL28548940 0.80
SCHEMBL13875717 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118724936-A Octamethyl hexaepoxy diphenyl heptasiloxane and preparation method thereof 武汉珈材科技有限公司 2024-10-01 CN claimed
CN-118580264-A Tetramethyl diepoxy diphenyl trisiloxane and preparation method thereof 武汉珈材科技有限公司 2024-09-03 CN claimed
CN-118580264-A Tetramethyl diepoxy diphenyl trisiloxane and preparation method thereof 武汉珈材科技有限公司 2024-09-03 CN disclosed
EP-2328953-A1 SILICON CONTAINING POLYMERIC MATERIALS Advanced Medical Optics, Inc. (US) 2011-06-08 EP disclosed
EP-2200536-A2 POLYMER COMPOSITIONS SUITABLE FOR INTRAOCULAR LENSES AND RELATED METHODS Abbott Medical Optics Inc. (US) 2010-06-30 EP disclosed
WO-2010027519-A1 SILICON CONTAINING POLYMERIC MATERIALS ADVANCED MEDICAL OPTICS (US) 2010-03-11 WO disclosed
WO-2009045902-A2 POLYMER COMPOSITIONS SUITABLE FOR INTRAOCULAR LENSES AND RELATED METHODS ADVANCED MEDICAL OPTICS, INC. (US) 2009-04-09 WO disclosed
EP-1583801-A1 ADDITION CROSS-LINKING TWO-COMPONENT SILICON MATERIALS WITH A HIGH SHORE D HARDNESS Kettenbach GmbH & CO. KG (DE) 2005-10-12 EP disclosed
WO-2004052994-A1 ADDITION CROSS-LINKING TWO-COMPONENT SILICON MATERIALS WITH A HIGH SHORE D HARDNESS KETTENBACH GMBH & CO. KG (DE) 2004-06-24 WO disclosed