Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | OGA | O60502 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17541709 | 0.81 | HRH3 (0.44) | RAB9ANPC1OGAMAPTALDH1A1 | |
| SCHEMBL19283645 | 0.80 | DPP4 (0.54) | RAB9ANPC1OGAMAPTALDH1A1 | |
| SCHEMBL11703124 | 0.80 | OGA (0.51) | RAB9ANPC1OGAMAPTALDH1A1 | |
| SCHEMBL18101352 | 0.79 | OGA (0.50) | RAB9ANPC1OGAMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL11700234 | 0.78 | OGA (0.50) | RAB9ANPC1OGAMAPTALDH1A1 | |
| SCHEMBL15341959 | 0.78 | OGA (0.56) | OGAMAPTALDH1A1HRH3LMNA | |
| SCHEMBL12869754 | 0.78 | OGA (0.49) | RAB9ANPC1OGAMAPTALDH1A1 | |
| SCHEMBL17541577 | 0.77 | LMNA (0.60) | RAB9ANPC1OGAMAPTALDH1A1 | |
| SCHEMBL19283656 | 0.77 | CTSB (0.50) | RAB9ANPC1OGAMAPTALDH1A1 | |
| SCHEMBL12506144 | 0.76 | OGA (0.45) | RAB9ANPC1OGAHRH3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3419976-A1 | ACID ADDITION SALTS OF PIPERAZINE DERIVATIVES | Asceneuron SA (CH) | 2019-01-02 | — | — | EP | disclosed |
| WO-2017144637-A1 | ACID ADDITION SALTS OF PIPERAZINE DERIVATIVES | ASCENEURON S. A. (CH) | 2017-08-31 | — | — | WO | disclosed |