Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | QPCT | Q16769 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17470122 | 0.85 | MAPT (0.51) | GAAHTTALDH1A1MAPTLMNA | |
| SCHEMBL19286292 | 0.82 | HTT (0.42) | GAAHTTALDH1A1MAPTLMNA | |
| SCHEMBL17470003 | 0.82 | GAA (0.38) | GAAALOX12HTTNPC1RAB9A | |
| SCHEMBL19286230 | 0.82 | MEN1 (0.42) | GAAALOX12HTTNPC1RAB9A | |
| SCHEMBL17470112 | 0.81 | HTT (0.37) | ALOX12HTTQPCT | |
| SCHEMBL17470166 | 0.79 | ALDH1A1 (0.41) | GAAALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL17470167 | 0.77 | ALPL (0.32) | — | |
| SCHEMBL17470043 | 0.76 | HTT (0.33) | HTTALDH1A1QPCT | |
| SCHEMBL17470110 | 0.75 | MTOR (0.41) | NPC1RAB9AMAPTLMNASMN1; SMN2 | |
| SCHEMBL15344715 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9744528-B2 | Metallorganocatalysis for asymmetric transformations | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-08-29 | — | — | US | disclosed |