Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ASPH | Q12797 | 1/20 | 0.41 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10287179 | 1.00 | LMNA (0.48) | LMNAALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL2847032 | 0.85 | LMNA (0.52) | LMNAALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL21675 | 0.81 | ALDH1A1 (0.52) | LMNAALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL8248592 | 0.81 | ALDH1A1 (0.52) | LMNAALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL13075266 | 0.81 | ALDH1A1 (0.52) | LMNAALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL1520851 | 0.79 | LMNA (0.52) | LMNAALDH1A1KDM4ETSHRHPGD | |
| Ammonia Solution, Strong SCHEMBL6810735 | 0.79 | ALDH1A1 (0.50) | LMNAALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL10709662 | 0.79 | LMNA (0.46) | LMNAALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL18539271 | 0.79 | LMNA (0.52) | LMNAALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL12312555 | 0.79 | LMNA (0.46) | LMNAALDH1A1KDM4ETSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9744528-B2 | Metallorganocatalysis for asymmetric transformations | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-08-29 | — | — | US | disclosed |