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Sugi Predict / Compounds / SCHEMBL19287635

SCHEMBL19287635

SCHEMBL19287635

c1ccc2c(c1)oc1c(-c3ccc(-n4c5ccccc5c5ccc6c7cc(-c8ccc9c%10ccc%11c%12ccccc%12oc%11c%10n(-c%10ccc(-c%11cccc%12c%11sc%11ccccc%11%12)cc%10)c9c8)ccc7oc6c54)cc3)cccc12

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ PRKDC P78527 8/20 0.37
▸ ALOX5 P09917 3/20 0.37
▸ PIK3CD O00329 2/20 0.34
▸ PIK3CB P42338 2/20 0.34
▸ BRD4 O60885 1/20 0.34
▸ PIK3CA P42336 1/20 0.34
▸ MTOR P42345 1/20 0.34
▸ PIK3CG P48736 1/20 0.34
▸ KCNH2 Q12809 1/20 0.34
▸ BRDT Q58F21 1/20 0.34
▸ ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17246079 0.92 ALOX5 (0.40) PRKDCALOX5PIK3CDPIK3CBBRD4
SCHEMBL24923149 0.91 ALOX5 (0.40) PRKDCALOX5PIK3CDPIK3CBBRD4
SCHEMBL24923245 0.91 PRKDC (0.33) PRKDCALOX5
SCHEMBL24676300 0.88 ALOX5 (0.41) PRKDCALOX5PIK3CDPIK3CBBRD4
SCHEMBL16675649 0.88 PRKDC (0.39) PRKDCALOX5PIK3CDPIK3CBBRD4
SCHEMBL12158911 0.88 ALOX5 (0.41) PRKDCALOX5PIK3CDPIK3CBBRD4
SCHEMBL15759674 0.88 ALOX5 (0.40) PRKDCALOX5PIK3CDPIK3CBBRD4
SCHEMBL15583068 0.87 ALOX5 (0.39) PRKDCALOX5PIK3CDPIK3CBBRD4
SCHEMBL15759677 0.87 ALOX5 (0.40) PRKDCALOX5PIK3CDPIK3CBBRD4
SCHEMBL15804132 0.87 ALOX5 (0.38) PRKDCALOX5PIK3CDPIK3CBBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10020459-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-07-10 — — US disclosed
US-9748510-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-08-29 — — US disclosed