SCHEMBL24923149

SCHEMBL24923149

c1ccc2c(c1)oc1c2ccc2c3ccccc3n(-c3ccc(-c4ccc(-c5cccc6c5sc5ccccc56)cc4)cc3)c21

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.40
PRKDC P78527 9/20 0.39
PIK3CD O00329 2/20 0.34
PIK3CB P42338 2/20 0.34
BRD4 O60885 1/20 0.34
PIK3CA P42336 1/20 0.34
MTOR P42345 1/20 0.34
PIK3CG P48736 1/20 0.34
KCNH2 Q12809 1/20 0.34
BRDT Q58F21 1/20 0.34
ESR2 Q92731 1/20 0.33
PARP14 Q460N5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17246079 0.99 ALOX5 (0.40) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL24676300 0.93 ALOX5 (0.41) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL17126191 0.93 PRKDC (0.35) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL17126168 0.93 PRKDC (0.35) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL15759677 0.92 ALOX5 (0.40) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL17705483 0.92 ALOX5 (0.43) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL16675649 0.91 PRKDC (0.39) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL19287635 0.91 PRKDC (0.37) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL15759674 0.91 ALOX5 (0.40) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL15583146 0.89 ALOX5 (0.40) ALOX5PRKDCPIK3CDPIK3CBBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230033529-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-02 US disclosed
US-20230027888-A1 ORGANIC ELECTROLUMINESCENT DEVICE, ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE, ELECTRONIC DEVICE AND COMPOUND IDEMITSU KOSAN CO.,LTD. (JP) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230027888-A1 ORGANIC ELECTROLUMINESCENT DEVICE, ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE, ELECTRONIC DEVICE AND COMPOUND HTR1D, EHD1, HTR3D ALOX5 2107/4885PRKDC 4367/4885PIK3CD 2039/4885
US-20230033529-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE LEF1, L1CAM, RAP1A ALOX5 2606/4885PRKDC 3590/4885PIK3CD 4649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.