Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 3/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL15563599 | 1.00 | MAPT (0.41) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL12153469 | 0.98 | MAPT (0.42) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL30685549 | 0.98 | MAPT (0.42) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL29843853 | 0.96 | MAPT (0.41) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL13416070 | 0.86 | GAA (0.44) | MAPTKDM4EALDH1A1GAAHPGD | |
| Iodide SCHEMBL1926231 | 0.85 | MAPT (0.36) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL13645631 | 0.82 | MAPT (0.37) | MAPTKDM4EALDH1A1GAAHPGD | |
| Iodide SCHEMBL4205929 | 0.82 | BRD4 (0.42) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL30261935 | 0.82 | SIGMAR1 (0.48) | MAPTKDM4EGAAHPGDATM | |
| SCHEMBL12153468 | 0.82 | SIGMAR1 (0.48) | MAPTKDM4EGAAHPGDATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250368670-A1 | TRANSITION METAL COMPLEX AND METHODS FOR ITS PREPARATION AND USE | SHANGHAI UNITED IMAGING MICROELECTRONICS TECH CO LTD (CN) | 2025-12-04 | — | — | US | disclosed |
| EP-4656647-A1 | TRANSITION METAL COMPLEX AND METHODS FOR ITS PREPARATION AND USE | Shanghai United Imaging Microelectronics Technology Co., Ltd. (CN) | 2025-12-03 | — | — | EP | disclosed |
| CN-118684716-A | Transition metal complex, preparation method and application thereof | 上海联影微电子科技有限公司 | 2024-09-24 | — | — | CN | disclosed |
| CN-115160374-A | Stable OLED materials and devices with improved stability | 通用显示公司 | 2022-10-11 | — | — | CN | disclosed |
| US-7956192-B2 | Carbene containing metal complexes as OLEDs | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2011-06-07 | — | — | US | disclosed |
| US-20090302754-A1 | CARBENE CONTAINING METAL COMPLEXES AS OLEDS | TSAI JUI-YI | 2009-12-10 | — | — | US | disclosed |
| US-7598388-B2 | Can stabily emit light with various spectra, including high energy blue spectra; tris(1-(2'-(9',9'-dimethyl)fluorenyl)-3-methyl-imidazolin-2-ylidene-C,C3') iridium(III); organic light emitting devices; combining L, a carbene ligand precursor, with an organic solvent at about 175 degrees C. | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2009-10-06 | — | — | US | disclosed |
| WO-2005113704-A2 | LUMINESCENT COMPOUNDS WITH CARBENE LIGANDS | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2005-12-01 | — | — | WO | disclosed |
| US-20050258742-A1 | Carbene containing metal complexes as OLEDs | UNIVERSAL DISPLAY CORPORATION | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090302754-A1 | CARBENE CONTAINING METAL COMPLEXES AS OLEDS | OPRD1, OGFRL1, OCIAD1 | MAPT 1897/4885KDM4E 4052/4885ALDH1A1 863/4885 |
| US-20250368670-A1 | TRANSITION METAL COMPLEX AND METHODS FOR ITS PREPARATION AND USE | AP2M1, AP1M1, AP3M1 | MAPT 4400/4885KDM4E 3376/4885ALDH1A1 2040/4885 |
| US-20050258742-A1 | Carbene containing metal complexes as OLEDs | OPRD1, OGFRL1, OCIAD1 | MAPT 1897/4885KDM4E 4052/4885ALDH1A1 863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.