Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1929256 | 1.00 | TP53 (0.38) | TP53 | |
| SCHEMBL16837588 | 0.83 | TP53 (0.36) | TP53 | |
| SCHEMBL7093529 | 0.78 | TP53 (0.35) | TP53 | |
| SCHEMBL6810509 | 0.78 | TP53 (0.35) | TP53 | |
| SCHEMBL6810609 | 0.78 | TP53 (0.35) | TP53 | |
| SCHEMBL7093528 | 0.78 | TP53 (0.35) | TP53 | |
| SCHEMBL7093912 | 0.78 | TP53 (0.35) | TP53 | |
| SCHEMBL6810503 | 0.78 | TP53 (0.35) | TP53 | |
| SCHEMBL7093527 | 0.78 | TP53 (0.35) | TP53 | |
| SCHEMBL7093910 | 0.78 | TP53 (0.35) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7955824-B2 | Methods of making epothilones | KOSAN BIOSCIENCES INCORPORATED (US) | 2011-06-07 | — | — | US | disclosed |
| US-20090076289-A1 | Methods of Making Epothilones | KOSAN BIOSCIENCES INCORPORATED (US) | 2009-03-19 | — | — | US | disclosed |
| WO-2008141234-A2 | METHODS OF MAKING EPOTHILONES | KOSAN BIOSCIENCES INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076289-A1 | Methods of Making Epothilones | DHPS, PPOX, EPOR | TP53 4576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.