Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24983142 | 0.81 | CA2 (0.44) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL16941472 | 0.81 | CA2 (0.44) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL932722 | 0.81 | CA2 (0.44) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL496774 | 0.79 | — | — | |
| SCHEMBL418534 | 0.79 | PTGS1 (0.53) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL1687008 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL5066620 | 0.77 | — | — | |
| SCHEMBL28038731 | 0.76 | PTGS1 (0.50) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL7869938 | 0.76 | PTGS1 (0.50) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL933723 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2861573-B1 | OXATHIAZINE DERIVATIVES AS ANTIBACTERIAL AND ANTICANCER AGENTS. | GEISTLICH PHARMA AG (CH) | 2017-08-30 | — | — | EP | disclosed |