SCHEMBL418534

SCHEMBL418534

O=S(=O)(O)CCOCCS(=O)(=O)O

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.53
PDE4A P27815 1/20 0.53
LMNA P02545 1/20 0.45
SLC6A6 P31641 1/20 0.45
CYP2C19 P33261 1/20 0.45
BLM P54132 1/20 0.45
APP P05067 1/20 0.41
SLC22A6 Q4U2R8 1/20 0.32
CA2 P00918 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
CA5A P35218 1/20 0.31
CA5B Q9Y2D0 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7869938 0.97 PTGS1 (0.50) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL28038731 0.97 PTGS1 (0.50) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL9842274 0.89 PTGS1 (0.43) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL375597 0.89 TSHR (0.53) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL263732 0.89 APP (0.46) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL8772862 0.87 LMNA (0.55) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL7527691 0.87 MEN1 (0.55) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL3488844 0.87 PTGS1 (0.42) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL7039096 0.87 TSHR (0.50) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL14599270 0.87 PTGS1 (0.42) PTGS1PDE4ALMNASLC6A6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 516 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210212321-A1 STABILIZED FUNGICIDAL COMPOSITION COMPRISING CYCLODEXTRIN BAYER CROPSCIENCE LP 2021-07-15 US claimed
EP-2152078-B1 FORMULATIONS CONTAINING CLOPIDOGREL AND SULFOALKYL ETHER CYCLODEXTRIN AND METHODS OF USE CYDEX PHARMACEUTICALS INC (US) 2021-01-13 EP claimed
CN-104800210-B Preparation comprising clopidogrel and sulfoalkyl ether cyclodextrin and its application method 锡德克斯药物公司 2019-08-06 CN claimed
US-9925274-B2 Delphinidin complex as an antiphlogistic or immunosuppressive active ingredient SAPIOTEC GMBH (DE) 2018-03-27 US claimed
EP-2919791-B1 DELPHINIDINCOMPLEX AS ANTIPHLOGISTIC OR IMMUNOSUPPRESSIVE AGENT SAPIOTEC GMBH (DE) 2017-03-22 EP claimed
US-20150306247-A1 DELPHINIDIN COMPLEX AS AN ANTIPHLOGISTIC OR IMMUNOSUPPRESSIVE ACTIVE INGREDIENT SAPIOTEC GMBH (DE) 2015-10-29 US claimed
CN-104800210-A Formulations containing clopidogrel and sulfoalkyl ether cyclodextrin and methods of use CYDEX PHARMACEUTICALS INC 2015-07-29 CN claimed
US-9085525-B2 Processes employing cyclodextrin derivative quaternary salts MATOS JOSE R (US) 2015-07-21 US claimed
CN-101686681-B Formulations comprising clopidogrel and sulfoalkyl ether cyclodextrins and methods of use thereof CYDEX PHARMACEUTICALS INC 2015-04-01 CN claimed
US-20140046061-A1 Processes Employing Cyclodextrin Derivative Quaternary Salts MATOS JOSE R (US) 2014-02-13 US claimed
EP-1742535-A2 TASTE-MASKED FORMULATIONS CONTAINING SERTRALINE AND SULFOALKYL ETHER CYCLODEXTRIN Cydex Inc. (US) 2007-01-17 EP claimed
WO-2005117911-A2 TASTE-MASKED FORMULATIONS CONTAINING SERTRALINE AND SULFOALKYL ETHER CYCLODEXTRIN CYDEX, INC. (US) 2005-12-15 WO claimed
WO-2005104712-A2 DPI FORMULATION CONTAINING SULFOALKYL ETHER CYCLODEXTRIN CYDEX, INC. (US) 2005-11-10 WO claimed
US-20050250738-A1 Taste-masked formulations containing sertraline and sulfoalkyl ether cyclodextrin CYDEX PHARMACEUTICALS, INC. 2005-11-10 US claimed
CN-1079824-C Ester oligomers suitable for use as soil release agents in detergent compositions PROCTER & GAMBLE (US) 2002-02-27 CN claimed
EP-0797655-B1 ESTER OLIGOMERS SUITABLE AS SOIL RELEASE AGENTS IN DETERGENT COMPOSITIONS PROCTER & GAMBLE (US) 1999-04-14 EP claimed
CN-1175277-A Ester oligomers suitable for use as soil release agents in detergent compositions PROCTER & GAMBLE (US) 1998-03-04 CN claimed
US-5691298-A DIHYDROXY OR POLYHYDROXY SULFONATES WITH ESTER GROUPS, TEREPHTHALOYL AND UNSULFONATE AND CAPPING GROUPS THE PROCTER & GAMBLE COMPANY (US) 1997-11-25 US claimed
EP-0797655-A2 ESTER OLIGOMERS SUITABLE AS SOIL RELEASE AGENTS IN DETERGENT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-10-01 EP claimed
WO-1996018715-A2 ESTER OLIGOMERS SUITABLE AS SOIL RELEASE AGENTS IN DETERGENT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1996-06-20 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210212321-A1 STABILIZED FUNGICIDAL COMPOSITION COMPRISING CYCLODEXTRIN CYP3A43, POR, CBR3 PTGS1 4019/4885PDE4A 963/4885LMNA 4024/4885
US-20150306247-A1 DELPHINIDIN COMPLEX AS AN ANTIPHLOGISTIC OR IMMUNOSUPPRESSIVE ACTIVE INGREDIENT HLA-DRB1, CD74, HLA-C PTGS1 2490/4885PDE4A 3162/4885LMNA 4668/4885
US-20140046061-A1 Processes Employing Cyclodextrin Derivative Quaternary Salts PICALM, SI, PDCD2L PTGS1 4149/4885PDE4A 2309/4885LMNA 4539/4885
US-20050250738-A1 Taste-masked formulations containing sertraline and sulfoalkyl ether cyclodextrin SORD, STS, SULT1A1 PTGS1 4572/4885PDE4A 991/4885LMNA 2917/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.