SCHEMBL19293447

SCHEMBL19293447

N[C@@H](CCC(=O)N[C@@H](CSSC[C@H](N)C(=O)O)C(=O)NCC(=O)O)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTGS1 P23219 1/20 0.70
▸ GSTK1 Q9Y2Q3 1/20 0.70
▸ GLO1 Q04760 4/20 0.61
▸ NOD1 Q9Y239 5/20 0.43
▸ FOLH1 Q04609 2/20 0.41
▸ GRM8 O00222 1/20 0.40
▸ GRM6 O15303 1/20 0.40
▸ GRIN2D O15399 1/20 0.40
▸ GRIN3B O60391 1/20 0.40
▸ GSR P00390 1/20 0.40
▸ CYP1A2 P05177 1/20 0.40
▸ GRIK1 P39086 1/20 0.40
▸ GRM5 P41594 1/20 0.40
▸ GRIA1 P42261 1/20 0.40
▸ GRIA2 P42262 1/20 0.40
▸ GRIA3 P42263 1/20 0.40
▸ SLC1A3 P43003 1/20 0.40
▸ SLC1A2 P43004 1/20 0.40
▸ SLC1A1 P43005 1/20 0.40
▸ GRIA4 P48058 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30382008 1.00 PTGS1 (0.70) PTGS1GSTK1GLO1NOD1FOLH1
SCHEMBL30443198 1.00 PTGS1 (0.70) PTGS1GSTK1GLO1NOD1FOLH1
SCHEMBL13930989 1.00 PTGS1 (0.70) PTGS1GSTK1GLO1NOD1FOLH1
SCHEMBL25770244 0.97 PTGS1 (0.70) PTGS1GSTK1GLO1NOD1FOLH1
Oxiglutatione SCHEMBL138746 0.97 PTGS1 (0.73) PTGS1GSTK1GLO1NOD1FOLH1
Oxiglutatione SCHEMBL16377441 0.97 PTGS1 (0.73) PTGS1GSTK1GLO1NOD1FOLH1
Oxiglutatione SCHEMBL19579378 0.97 PTGS1 (0.73) PTGS1GSTK1GLO1NOD1FOLH1
Oxiglutatione SCHEMBL13561367 0.97 PTGS1 (0.73) PTGS1GSTK1GLO1NOD1FOLH1
Oxiglutatione SCHEMBL18744121 0.97 PTGS1 (0.73) PTGS1GSTK1GLO1NOD1FOLH1
Oxiglutatione SCHEMBL4362052 0.97 PTGS1 (0.73) PTGS1GSTK1GLO1NOD1FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3194027-B1 COMPOSITIONS FOR USE IN TREATING PSYCHOTIC DISORDERS SOUND PHARMACEUTICALS INCORPORATED (US) 2026-02-11 — — EP disclosed
US-12427138-B2 Treatment of Meniere's disease SOUND PHARMACEUTICALS INCORPORATED (US) 2025-09-30 — — US disclosed
CN-119827684-A Beijing white pear origin identification method based on metabonomics technology 北京市农林科学院 2025-04-15 — — CN disclosed
EP-4461360-A2 TREATMENT OF MENIERE'S DISEASE Sound Pharmaceuticals Incorporated (US) 2024-11-13 — — EP disclosed
CN-117969859-B Metabolic biomarker for polycystic ovary syndrome and application thereof 山东大学 2024-09-06 — — CN disclosed
EP-3458045-B1 EBSELEN FOR USE IN THE TREATMENT OF MENIERE'S DISEASE SOUND PHARMACEUTICALS INCORPORATED (US) 2024-08-21 — — EP disclosed
US-20240050409-A1 Methods and Compositions for Treating Psychotic Disorders SOUND PHARMACEUTICALS INCORPORATED 2024-02-15 — — US disclosed
US-20240041851-A1 METHOD OF TREATING AND PREVENTING VIRAL INFECTION NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-02-08 — — US disclosed
US-20230384327-A1 GUT MICROBIOTA-RELATED METHODS FOR TREATING DEMENTIA AND AGE-DEPENDENT COGNITIVE DECLINE ALBERT-LUDWIGS-UNIVERSITAT FREIBURG (DE) 2023-11-30 — — US disclosed
US-20230384327-A1 GUT MICROBIOTA-RELATED METHODS FOR TREATING DEMENTIA AND AGE-DEPENDENT COGNITIVE DECLINE ALBERT-LUDWIGS-UNIVERSITAT FREIBURG (DE) 2023-11-30 — — US disclosed
WO-2023116664-A1 PREPARATION METHOD FOR OXIDIZED GLUTATHIONE AND CRYSTAL FORM AND IMPURITY THEREOF 沈阳兴齐眼药股份有限公司 2023-06-29 — — WO disclosed
US-20210379017-A1 Methods and Compositions for Treating Psychotic Disorders SOUND PHARMACEUTICALS INCORPORATED 2021-12-09 — — US disclosed
WO-2017201318-A1 TREATMENT OF MENIERE'S DISEASE SOUND PHARMACEUTICALS INCORPORATED (US) 2017-11-23 — — WO disclosed
US-20170246148-A1 Methods and Compositions for Treating Psychotic Disorders SOUND PHARMACEUTICALS INCORPORATED 2017-08-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210379017-A1 Methods and Compositions for Treating Psychotic Disorders GPX4, GPX1, GSR PTGS1 242/4885GSTK1 15/4885GLO1 184/4885
US-12427138-B2 Treatment of Meniere's disease GPX1, GSR, GPX4 PTGS1 77/4885GSTK1 58/4885GLO1 390/4885
US-20240041851-A1 METHOD OF TREATING AND PREVENTING VIRAL INFECTION DHFR, FAH, HAVCR2 PTGS1 771/4885GSTK1 201/4885GLO1 90/4885
US-20240050409-A1 Methods and Compositions for Treating Psychotic Disorders GPX4, GPX1, GSR PTGS1 242/4885GSTK1 15/4885GLO1 184/4885
US-20170246148-A1 Methods and Compositions for Treating Psychotic Disorders GPX4, GPX1, GSR PTGS1 235/4885GSTK1 14/4885GLO1 182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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