Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1605131 | 0.89 | HTR1A (0.30) | HTR1APTGS2 | |
| SCHEMBL5324562 | 0.86 | LMNA (0.33) | LMNA | |
| SCHEMBL16927485 | 0.82 | LMNA (0.30) | LMNA | |
| SCHEMBL1606817 | 0.81 | CA14 (0.30) | — | |
| SCHEMBL561418 | 0.77 | — | — | |
| SCHEMBL561420 | 0.76 | — | — | |
| SCHEMBL126593 | 0.75 | CA12 (0.33) | LMNA | |
| SCHEMBL560914 | 0.75 | — | — | |
| SCHEMBL560916 | 0.75 | — | — | |
| SCHEMBL17187425 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014692-B1 | Polyisocyanates containing allophanate and silane groups | COVESTRO DEUTSCHLAND AG (DE) | 2016-02-10 | — | — | EP | disclosed |
| US-7956209-B2 | Polyisocyanates containing allophanate and silane groups | BAYER MATERIALSCIENCE AG (DE) | 2011-06-07 | — | — | US | disclosed |
| US-20090018302-A1 | POLYISOCYANATES CONTAINING ALLOPHANATE AND SILANE GROUPS | BAYER MATERIALSCIENCE AG (DE) | 2009-01-15 | — | — | US | disclosed |
| EP-2014692-A2 | Polyisocyanates containing allophanate and silane groups | Bayer MaterialScience AG (DE) | 2009-01-14 | — | — | EP | disclosed |