Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3771299 | 0.82 | PPARG (0.45) | AGTR1AGTR2PPARG | |
| SCHEMBL1926924 | 0.79 | AGTR1 (0.39) | AGTR1AGTR2 | |
| SCHEMBL18069704 | 0.78 | NOTUM (0.39) | — | |
| SCHEMBL7008748 | 0.76 | PPARG (0.45) | AGTR1AGTR2PPARG | |
| SCHEMBL7015044 | 0.75 | PDE4A (0.55) | PPARG | |
| SCHEMBL9485855 | 0.74 | AGTR1 (0.43) | AGTR1AGTR2PPARG | |
| SCHEMBL7021255 | 0.73 | AGTR2 (0.40) | AGTR1AGTR2 | |
| SCHEMBL31069898 | 0.73 | DCUN1D1 (0.33) | — | |
| SCHEMBL9284864 | 0.73 | DCUN1D1 (0.33) | AGTR1 | |
| SCHEMBL653868 | 0.73 | MME (0.40) | AGTR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7956054-B2 | Dual-acting pyrazole antihypertensive agents | THERAVANCE, INC. (US) | 2011-06-07 | — | — | US | disclosed |