SCHEMBL19296162

SCHEMBL19296162

C[C@@]1(C(=O)O)CCCC[C@H]1C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 1/20 0.39
SLC1A1 P43005 1/20 0.39
LMNA P02545 3/20 0.37
POLB P06746 1/20 0.37
HSD11B1 P28845 1/20 0.36
FFAR3 O14843 1/20 0.36
F10 P00742 2/20 0.35
GRM2 Q14416 2/20 0.34
GRM3 Q14832 2/20 0.34
GRM4 Q14833 2/20 0.34
CYP2C19 P33261 2/20 0.34
MTOR P42345 2/20 0.34
CYP1A2 P05177 1/20 0.34
ALOX15 P16050 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
GRM8 O00222 1/20 0.34
GRM6 O15303 1/20 0.34
GRM5 P41594 1/20 0.34
GRM1 Q13255 1/20 0.34
PLCB1 Q9NQ66 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL158905 1.00 SLC1A2 (0.39) SLC1A2SLC1A1LMNAPOLBHSD11B1
SCHEMBL28968459 0.98 SLC1A2 (0.38) SLC1A2SLC1A1LMNAPOLBHSD11B1
SCHEMBL28968524 0.98 SLC1A2 (0.38) SLC1A2SLC1A1LMNAPOLBHSD11B1
SCHEMBL28968457 0.98 SLC1A2 (0.38) SLC1A2SLC1A1LMNAPOLBHSD11B1
SCHEMBL28968468 0.98 SLC1A2 (0.38) SLC1A2SLC1A1LMNAPOLBHSD11B1
SCHEMBL28968519 0.98 SLC1A2 (0.38) SLC1A2SLC1A1LMNAPOLBHSD11B1
Hydrochloric Acid SCHEMBL29273218 0.98 SLC1A2 (0.38) SLC1A2SLC1A1LMNAPOLBHSD11B1
SCHEMBL28968513 0.98 SLC1A2 (0.38) SLC1A2SLC1A1LMNAPOLBHSD11B1
SCHEMBL28968495 0.98 SLC1A2 (0.38) SLC1A2SLC1A1LMNAPOLBHSD11B1
Cyclopentane SCHEMBL6061198 0.96 LMNA (0.38) SLC1A2SLC1A1LMNAPOLBHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10426770-B2 Process for the preparation of Lurasidone hydrochloride Jubilant Generics Limited (IN) 2019-10-01 US disclosed
US-20170246165-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF LURASIDONE HYDROCHLORIDE Jubilant Generics Limited (IN) 2017-08-31 US disclosed
US-20170246165-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF LURASIDONE HYDROCHLORIDE Jubilant Generics Limited (IN) 2017-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170246165-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF LURASIDONE HYDROCHLORIDE FFAR3, FAR1, PRLHR SLC1A2 1198/4885SLC1A1 1119/4885LMNA 3360/4885
US-10426770-B2 Process for the preparation of Lurasidone hydrochloride FFAR3, REN, LSS SLC1A2 1539/4885SLC1A1 1412/4885LMNA 3313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.