SCHEMBL1929660

SCHEMBL1929660

CC(C)c1[nH]nnc1C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 7/20 0.36
HCAR3 P49019 2/20 0.36
HAO1 Q9UJM8 1/20 0.31
PRKAB2 O43741 1/20 0.30
PRKAG1 P54619 1/20 0.30
PRKAA2 P54646 1/20 0.30
PRKAA1 Q13131 1/20 0.30
PRKAG3 Q9UGI9 1/20 0.30
PRKAG2 Q9UGJ0 1/20 0.30
PRKAB1 Q9Y478 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29028193 0.81 HCAR3 (0.41) HCAR2HCAR3
SCHEMBL23679986 0.81 HCAR2 (0.31) HCAR2
SCHEMBL1930145 0.71
SCHEMBL29569474 0.70 CES2 (0.39) HAO1
SCHEMBL22637676 0.69 HCAR2 (0.52) HCAR2HCAR3PRKAB2PRKAG1PRKAA2
SCHEMBL32678648 0.69 HCAR2 (0.41) HCAR2HCAR3PRKAB2PRKAG1PRKAA2
SCHEMBL32678650 0.69 HCAR2 (0.41) HCAR2HCAR3PRKAB2PRKAG1PRKAA2
SCHEMBL12050672 0.69
SCHEMBL17479339 0.68 HCAR2 (0.58) HCAR2HCAR3PRKAB2PRKAG1PRKAA2
SCHEMBL30300414 0.68 HCAR2 (0.58) HCAR2HCAR3PRKAB2PRKAG1PRKAA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8083964-B2 Using amino acid derivative and surfactant as polishing mixture FUJIFILM CORPORATION (JP) 2011-12-27 US disclosed
US-8083964-B2 Using amino acid derivative and surfactant as polishing mixture FUJIFILM CORPORATION (JP) 2011-12-27 US disclosed
US-7956070-B2 Piperidines as chemokine modulators (CCR) ASTRAZENECA AB (SE) 2011-06-07 US disclosed
US-20100330809-A1 POLISHING LIQUID FOR METALS FUJIFILM CORPORATION (JP) 2010-12-30 US disclosed
US-20100330809-A1 POLISHING LIQUID FOR METALS FUJIFILM CORPORATION (JP) 2010-12-30 US disclosed
US-20080242090-A1 Using amino acid derivative and surfactant as polishing mixture FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
US-20080242090-A1 Using amino acid derivative and surfactant as polishing mixture FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
US-20080206995-A1 METAL-POLISHING LIQUID AND POLISHING METHOD THEREWITH FUJIFILM CORPORATION (JP) 2008-08-28 US disclosed
US-20080206995-A1 METAL-POLISHING LIQUID AND POLISHING METHOD THEREWITH FUJIFILM CORPORATION (JP) 2008-08-28 US disclosed
US-20070200089-A1 Polishing liquid for metals FUJIFILM CORPORATION 2007-08-30 US disclosed
US-20070200089-A1 Polishing liquid for metals FUJIFILM CORPORATION 2007-08-30 US disclosed
US-20070054924-A1 Novel piperidines as chemokine modulators (ccr) ASTRAZENECA AB (SE) 2007-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070054924-A1 Novel piperidines as chemokine modulators (ccr) CCR3, CCR1, CCR4 HCAR2 103/4885HCAR3 32/4885HAO1 4350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.