Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19300267 | 0.89 | OGA (0.66) | MEN1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL19300079 | 0.87 | OGA (0.67) | MEN1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL19300265 | 0.86 | OGA (0.66) | MEN1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL11520142 | 0.85 | MEN1 (0.61) | MEN1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL19481321 | 0.83 | MEN1 (0.61) | MEN1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL23653068 | 0.82 | ALDH1A1 (0.54) | MEN1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL12298740 | 0.79 | GLS (0.55) | MEN1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL11520225 | 0.78 | CYP2D6 (0.55) | MEN1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL17551140 | 0.77 | OGA (0.79) | OGA | |
| SCHEMBL11517028 | 0.77 | MEN1 (0.59) | MEN1CYP1A2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280381-A1 | MEDICAMENTS COMPRISING GLYCOSIDASE INHIBITORS | ASCENEURON SA (CH) | 2023-01-12 | — | — | WO | disclosed |
| EP-3419976-B1 | ACID ADDITION SALTS OF PIPERAZINE DERIVATIVES | ASCENEURON SA (CH) | 2021-04-07 | — | — | EP | disclosed |
| WO-2017144637-A1 | ACID ADDITION SALTS OF PIPERAZINE DERIVATIVES | ASCENEURON S. A. (CH) | 2017-08-31 | — | — | WO | disclosed |