Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | RARB | P10826 | 6/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.50 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.50 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27705274 | 0.93 | SMN1; SMN2 (0.60) | SMN1; SMN2TSHRRARBPTGER4PTGER2 | |
| SCHEMBL19301332 | 0.86 | RARB (0.59) | SMN1; SMN2TSHRRARBHDAC8PTGER1 | |
| SCHEMBL1982703 | 0.84 | HDAC8 (0.67) | SMN1; SMN2TSHRRARBHDAC8PTGER1 | |
| Benzoic Acid SCHEMBL5085787 | 0.82 | TSHR (0.58) | SMN1; SMN2TSHRMAPTKMT2ANPC1 | |
| SCHEMBL133470 | 0.82 | RARB (0.68) | TSHRRARBHDAC8PTGER1PTGER4 | |
| SCHEMBL27705266 | 0.81 | FOLH1 (0.59) | SMN1; SMN2TSHRMAPTKMT2ANPC1 | |
| SCHEMBL1980515 | 0.80 | RARB (0.65) | SMN1; SMN2RARBHDAC8PTGER1PTGER4 | |
| SCHEMBL27705270 | 0.79 | FOLH1 (0.58) | SMN1; SMN2TSHRMAPTKMT2ANPC1 | |
| SCHEMBL1296456 | 0.79 | FOLH1 (0.61) | KMT2AHDAC1BCL2 | |
| SCHEMBL1980273 | 0.79 | FOLH1 (0.61) | SMN1; SMN2HDAC8KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170247688-A1 | ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES | NUEVOLUTION A/S (DK) | 2017-08-31 | — | — | US | disclosed |