Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 2/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19301511 | 0.93 | SMN1; SMN2 (0.57) | SMN1; SMN2TSHRNPC1RAB9AFFAR1 | |
| SCHEMBL27705266 | 0.87 | FOLH1 (0.59) | SMN1; SMN2TSHRNPC1RAB9ATP53 | |
| SCHEMBL27705270 | 0.86 | FOLH1 (0.58) | SMN1; SMN2TSHRNPC1RAB9ATP53 | |
| SCHEMBL1296456 | 0.85 | FOLH1 (0.61) | HDAC1PPARABCL2FOLH1 | |
| Benzoic Acid SCHEMBL5085787 | 0.85 | TSHR (0.58) | SMN1; SMN2TSHRNPC1RAB9ATP53 | |
| SCHEMBL27686277 | 0.85 | ALDH1A1 (0.56) | SMN1; SMN2TSHRNPC1RAB9AHPGD | |
| SCHEMBL27686300 | 0.84 | HDAC1 (0.46) | SMN1; SMN2TSHRFFAR1HDAC1TP53 | |
| Hydrochloric Acid SCHEMBL7138106 | 0.84 | FOLH1 (0.59) | HDAC1PPARABCL2FOLH1 | |
| SCHEMBL9454318 | 0.82 | TSHR (0.59) | TSHRFFAR1HPGDHSD17B10DAO | |
| SCHEMBL1926270 | 0.82 | HDAC1 (0.64) | TSHRFFAR1HDAC1TP53DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101955470-A | Glutamate receptor potentiators | LILLY CO ELI | 2011-01-26 | — | — | CN | disclosed |
| CN-101061106-B | Glutamate receptor potentiators | LILLY CO ELI | 2010-09-29 | — | — | CN | disclosed |
| CN-101061106-A | Glutamate receptor potentiators | LILLY CO ELI (US) | 2007-10-24 | — | — | CN | disclosed |