Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM2 | O94759 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19302704 | 0.90 | HINT1 (0.55) | TRPM2 | |
| SCHEMBL19302750 | 0.88 | TRPM2 (0.64) | TRPM2 | |
| SCHEMBL19302683 | 0.86 | TRPM2 (0.72) | TRPM2 | |
| SCHEMBL19302799 | 0.86 | TRPM2 (0.64) | TRPM2 | |
| SCHEMBL19302894 | 0.86 | TRPM2 (0.68) | TRPM2 | |
| SCHEMBL19302915 | 0.86 | TRPM2 (0.69) | TRPM2 | |
| SCHEMBL19303080 | 0.85 | TRPM2 (0.47) | TRPM2 | |
| SCHEMBL19302684 | 0.85 | TRPM2 (0.70) | TRPM2 | |
| SCHEMBL19302806 | 0.85 | TRPM2 (0.64) | TRPM2 | |
| SCHEMBL20508954 | 0.84 | TRPM2 (0.63) | TRPM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017059411-A9 | INHIBITORS OF MENAQUINONE BIOSYNTHESIS | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2017-08-31 | — | — | WO | disclosed |