SCHEMBL1930320

SCHEMBL1930320

Sc1ccccc1Oc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.52
TSHR P16473 2/20 0.52
LMNA P02545 1/20 0.48
GAA P10253 1/20 0.48
KMT2A Q03164 1/20 0.48
HRH1 P35367 1/20 0.45
CTNNB1 P35222 1/20 0.45
ALDH1A1 P00352 2/20 0.44
HTT P42858 2/20 0.44
MAPK1 P28482 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
SLC6A2 P23975 2/20 0.44
SLC6A4 P31645 2/20 0.44
RIPK1 Q13546 1/20 0.44
HPGD P15428 1/20 0.44
KDM1A O60341 2/20 0.42
HTR1A P08908 1/20 0.42
SLC6A3 Q01959 1/20 0.42
DPP4 P27487 1/20 0.42
NR1H2 P55055 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30032880 1.00 LTA4H (0.52) LTA4HTSHRLMNAGAAKMT2A
Hydrogen Sulfide SCHEMBL27890272 0.98 LTA4H (0.50) LTA4HTSHRLMNAGAAKMT2A
SCHEMBL9296113 0.84 TSHR (0.46) LTA4HTSHRLMNAGAAKMT2A
SCHEMBL8521080 0.84 ALDH1A1 (0.49) LMNAKMT2AALDH1A1HTTMAPK1
SCHEMBL31037154 0.84 CA1 (0.38) LTA4HTSHRLMNAGAAKMT2A
SCHEMBL9820616 0.84 CA1 (0.38) LTA4HTSHRLMNAGAAKMT2A
SCHEMBL1929944 0.82 ALDH1A1 (0.39) LTA4HTSHRLMNAGAAKMT2A
SCHEMBL10363194 0.82 NCOA1 (0.56) TSHRGAAKMT2AHRH1ALDH1A1
SCHEMBL51822 0.81 LTA4H (0.69) LTA4HTSHRLMNAGAAKMT2A
SCHEMBL9557268 0.81 NCOA1 (0.46) LTA4HTSHRLMNAGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114478150-B S-deuterated methyl-aryl sulfonyl thioester compound and synthetic method and application thereof 浙江工业大学 2024-04-09 CN disclosed
US-20240110071-A1 Ultraviolet-Curable Water-Based Ink, Dispersion, Ultraviolet-Curable Water-Based Composition, and Printed Matter MITSUBISHI CHEMICAL CORPORATION (JP) 2024-04-04 US disclosed
EP-4328246-A1 ULTRAVIOLET-CURABLE AQUEOUS INK, DISPERSION, ULTRAVIOLET-CURABLE AQUEOUS COMPOSITION, AND PRINTED MATTER Mitsubishi Chemical Corporation (JP) 2024-02-28 EP disclosed
CN-117242140-A Ultraviolet-curable aqueous ink, dispersion, ultraviolet-curable aqueous composition, and printed matter 三菱化学株式会社 2023-12-15 CN disclosed
CN-116621745-A (2-phenoxyphenyl) phenyl thioether compound and synthesis method thereof 华北水利水电大学 2023-08-22 CN disclosed
CN-114478150-A S-deuterated methyl-aryl sulfonyl thioester compound and synthesis method and application thereof 浙江工业大学 2022-05-13 CN disclosed
US-9908846-B2 Composition, synthesis, and use of new arylsulfonyl isonitriles DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) 2018-03-06 US disclosed
US-9908846-B2 Composition, synthesis, and use of new arylsulfonyl isonitriles DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) 2018-03-06 US disclosed
US-9908846-B2 Composition, synthesis, and use of new arylsulfonyl isonitriles DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) 2018-03-06 US disclosed
US-9481645-B2 Composition, synthesis, and use of a new class of isonitriles DUQUESNE UNIVERSITY OF THE HOLY GHOST (US) 2016-11-01 US disclosed
WO-1999067255-A1 PROPENYL CEPHALOSPORIN DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 1999-12-29 WO disclosed
WO-1999025687-A1 AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR G.D. SEARLE & CO. (US) 1999-05-27 WO disclosed
WO-1998039316-A1 N-HYDROXY 4-SULFONYL BUTANAMIDE COMPOUNDS MONSANTO COMPANY (US) 1998-09-11 WO disclosed
US-5124060-A Containing fluorinated surfactant NIPPON SEIKO KABUSHIKI KAISHA (JP) 1992-06-23 US disclosed
US-5066795-A Reagent for perfluoroalkylation, heterocyclic sulfur or selenium compounds SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-11-19 US disclosed
EP-0382206-A1 Perfluoroalkyl-containing compound SAGAMI CHEMICAL RESEARCH CENTER (JP) 1990-08-16 EP disclosed
US-4547553-A CROSSLINKED SOLVENT RESISTANT THERMOPLASTIC RESIN THE BOEING COMPANY (US) 1985-10-15 US disclosed
EP-0024683-B1 PROCESS FOR THE PREPARATION OF CHLOROTHIOFORMATES HOECHST AKTIENGESELLSCHAFT (DE) 1982-10-27 EP disclosed
US-4340746-A CATALYZED REACTION OF MERCAPTANS WITH PHOSGENE HOECHST AKTIENGESELLSCHAFT (DE) 1982-07-20 US disclosed
EP-0024683-A1 Process for the preparation of chlorothioformates HOECHST AKTIENGESELLSCHAFT (DE) 1981-03-11 EP disclosed