Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.81 |
| ▸ | MEN1 | O00255 | 4/20 | 0.81 |
| ▸ | HPGD | P15428 | 4/20 | 0.81 |
| ▸ | MAPT | P10636 | 4/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.81 |
| ▸ | CES1 | P23141 | 1/20 | 0.81 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.63 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dibenzoylmethane SCHEMBL39582 | 0.90 | MEN1 (1.00) | KMT2AMEN1HPGDMAPTMAPK1 | |
| Dibenzoylmethane SCHEMBL10356288 | 0.90 | MEN1 (1.00) | KMT2AMEN1HPGDMAPTMAPK1 | |
| Dibenzoylmethane SCHEMBL1704711 | 0.90 | MEN1 (1.00) | KMT2AMEN1HPGDMAPTMAPK1 | |
| SCHEMBL28972855 | 0.90 | KMT2A (0.65) | KMT2AMEN1HPGDMAPTMAPK1 | |
| SCHEMBL28972880 | 0.90 | MEN1 (0.65) | KMT2AMEN1HPGDMAPTMAPK1 | |
| Dibenzoylmethane SCHEMBL28463188 | 0.88 | KMT2A (0.85) | KMT2AMEN1HPGDMAPTMAPK1 | |
| Dibenzoylmethane SCHEMBL11587518 | 0.87 | MEN1 (0.94) | KMT2AMEN1HPGDMAPTMAPK1 | |
| Dibenzoylmethane SCHEMBL9276614 | 0.87 | MEN1 (0.94) | KMT2AMEN1HPGDMAPTMAPK1 | |
| Dibenzoylmethane SCHEMBL11909772 | 0.87 | MEN1 (0.94) | KMT2AMEN1HPGDMAPTMAPK1 | |
| Dibenzoylmethane SCHEMBL21597905 | 0.87 | MEN1 (0.94) | KMT2AMEN1HPGDMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114307890-B | Bamboo capsule and preparation method and application thereof | 中国林业科学研究院木材工业研究所 | 2022-12-23 | — | — | CN | claimed |
| CN-114307890-A | Bamboo capsule and preparation method and application thereof | 中国林业科学研究院木材工业研究所 | 2022-04-12 | — | — | CN | claimed |
| US-9874566-B2 | Compositions and methods for making and using oxygen sensing nanofibers and scaffolds | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2018-01-23 | — | — | US | claimed |
| US-20160041177-A1 | COMPOSITIONS AND METHODS FOR MAKING AND USING OXYGEN SENSING NANOFIBERS AND SCAFFOLDS | Univ Virginia Patent Found (US) | 2016-02-11 | — | — | US | claimed |
| WO-2023064887-A1 | MECHANOCHEMICAL DYNAMIC THERAPY FOR FOCAL CANCER TREATMENT | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-04-20 | — | — | WO | disclosed |
| US-20230119684-A1 | MECHANOCHEMICAL DYNAMIC FOR FOCAL CANCER TREATMENT | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-04-20 | — | — | US | disclosed |
| CN-115677739-A | Preparation method of O, O-boron difluoride complex | 华南理工大学 | 2023-02-03 | — | — | CN | disclosed |
| CN-114307890-B | Bamboo capsule and preparation method and application thereof | 中国林业科学研究院木材工业研究所 | 2022-12-23 | — | — | CN | disclosed |
| CN-114307890-A | Bamboo capsule and preparation method and application thereof | 中国林业科学研究院木材工业研究所 | 2022-04-12 | — | — | CN | disclosed |
| US-20180355242-A1 | OXYGEN SENSING DIFLUOROBORON B-DIKETONATE POLYLACTIDE MATERIALS FOR WOUND IMAGING | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-12-13 | — | — | US | disclosed |
| US-10149644-B2 | Curcumin derivatives for amyloid-β plaque imaging | THE GENERAL HOSPITAL CORPORATION (US) | 2018-12-11 | — | — | US | disclosed |
| US-9874566-B2 | Compositions and methods for making and using oxygen sensing nanofibers and scaffolds | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2018-01-23 | — | — | US | disclosed |
| US-20150087937-A1 | CURCUMIN DERIVATIVES FOR AMYLOID-BETA PLAQUE IMAGING | MASSACHUSETTS GENERAL HOSPITAL (US) | 2015-03-26 | — | — | US | disclosed |
| US-20130210053-A1 | MECHANOCHROMIC LUMINESCENT DIFLUOROBORON BETA-DIKETONATES | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2013-08-15 | — | — | US | disclosed |
| US-20110208064-A1 | Curcumin Derivatives for Amyloid-Beta Plaque Imaging | THE GENERAL HOSPITAL CORPORATION | 2011-08-25 | — | — | US | disclosed |
| WO-2011068537-A2 | MECHANOCHROMIC LUMINESCENT DIFLUOROBORON BETA-DIKETONATES | FRASER CASSANDRA L (US) | 2011-06-09 | — | — | WO | disclosed |
| US-7955861-B2 | Luminescent diketonate polymers | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2011-06-07 | — | — | US | disclosed |
| WO-2010017094-A2 | CURCUMIN DERIVATIVES FOR AMYLOID-β PLAQUE IMAGING | THE GENERAL HOSPITAL CORPORATION (US) | 2010-02-11 | — | — | WO | disclosed |
| US-20090137057-A1 | LUMINESCENT DIKETONATE POLYMERS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2009-05-28 | — | — | US | disclosed |
| WO-2007143209-A2 | LUMINESCENT DIKETONATE POLYMERS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2007-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150087937-A1 | CURCUMIN DERIVATIVES FOR AMYLOID-BETA PLAQUE IMAGING | APP, BACE1, PSEN1 | KMT2A 2570/4885MEN1 990/4885HPGD 2036/4885 |
| US-10149644-B2 | Curcumin derivatives for amyloid-β plaque imaging | APP, BACE1, PSEN1 | KMT2A 2578/4885MEN1 955/4885HPGD 1971/4885 |
| US-20110208064-A1 | Curcumin Derivatives for Amyloid-Beta Plaque Imaging | APP, BACE1, PSEN1 | KMT2A 2570/4885MEN1 990/4885HPGD 2036/4885 |
| US-20160041177-A1 | COMPOSITIONS AND METHODS FOR MAKING AND USING OXYGEN SENSING NANOFIBERS AND SCAFFOLDS | ILK, HIF1A, TNNI3 | KMT2A 4810/4885MEN1 3310/4885HPGD 905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.