Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 3/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylamine SCHEMBL2799213 | 0.93 | FDPS (0.35) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL692449 | 0.91 | — | — | |
| Ethylenediamine SCHEMBL5701197 | 0.86 | LMNA (0.30) | FDPS | |
| SCHEMBL2058636 | 0.85 | TSHR (0.37) | TSHRFDPSSMPD1 | |
| SCHEMBL6037308 | 0.83 | TSHR (0.42) | TSHRFDPSSMPD1 | |
| SCHEMBL5843389 | 0.83 | TSHR (0.42) | TSHRFDPSSMPD1 | |
| SCHEMBL10603829 | 0.83 | TSHR (0.42) | TSHRFDPSSMPD1 | |
| SCHEMBL4534259 | 0.83 | TSHR (0.42) | TSHRFDPSSMPD1 | |
| SCHEMBL9016161 | 0.83 | TSHR (0.42) | TSHRFDPSSMPD1 | |
| SCHEMBL159036 | 0.83 | TSHR (0.42) | TSHRFDPSSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2169467-B1 | Toner for developing electrostatic image, developer for developing electrostatic image, toner cartridge, process cartridge, and image forming apparatus | FUJI XEROX CO LTD (JP) | 2012-06-13 | — | — | EP | disclosed |
| US-7955773-B2 | Toner for developing electrostatic image, developer for developing electrostatic image, toner cartridge, process cartridge, and image forming apparatus | FUJI XEROX CO., LTD. (JP) | 2011-06-07 | — | — | US | disclosed |
| US-20100081074-A1 | TONER FOR DEVELOPING ELECTROSTATIC IMAGE, DEVELOPER FOR DEVELOPING ELECTROSTATIC IMAGE, TONER CARTRIDGE, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS | FUJI XEROX CO., LTD. (JP) | 2010-04-01 | — | — | US | disclosed |
| EP-2169467-A1 | Toner for developing electrostatic image, developer for developing electrostatic image, toner cartridge, process cartridge, and image forming apparatus | Fuji Xerox Co., Ltd. (JP) | 2010-03-31 | — | — | EP | disclosed |
| EP-0368279-B1 | Silane coupling agent and glass fiber product for laminates | NITTO BOSEKI CO LTD (JP) | 2000-03-15 | — | — | EP | disclosed |
| US-5149839-A | Improved impregnation, solvent resistance, heat resistance and low water absoprtion properties | NITTO BOSEKI CO., LTD. (JP) | 1992-09-22 | — | — | US | disclosed |
| US-5069971-A | With epoxy resins, printed circuits, diaminoalklyalkoxysilane | NITTO BOSEKI CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |
| EP-0368279-A1 | Silane coupling agent and glass fiber product for laminates | NITTO BOSEKI CO., LTD. (JP) | 1990-05-16 | — | — | EP | disclosed |