Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL19307331

C=CCc1cccc(CCl)c1CC=C.N

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.46
GABRB2 P47870 2/20 0.46
AKR1B1 P15121 1/20 0.36
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
MAPT P10636 3/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MAPK1 P28482 1/20 0.34
ALDH1A1 P00352 4/20 0.33
GAA P10253 2/20 0.33
LMNA P02545 1/20 0.33
KDM4E B2RXH2 2/20 0.32
HSD17B10 Q99714 2/20 0.32
TDP1 Q9NUW8 1/20 0.31
CASP1 P29466 1/20 0.31
ADRA2A P08913 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28175466 0.90 GABRA1 (0.47) GABRA1GABRB2AKR1B1MEN1KMT2A
SCHEMBL18136 0.87 GABRA1 (0.56) GABRA1GABRB2AKR1B1MEN1KMT2A
SCHEMBL28398132 0.85 GABRA1 (0.50) GABRA1GABRB2AKR1B1MEN1KMT2A
Ammonia Solution, Strong SCHEMBL11203810 0.83 GABRA1 (0.48) GABRA1GABRB2AKR1B1MEN1KMT2A
SCHEMBL7705575 0.82 GABRA1 (0.34) GABRA1GABRB2
SCHEMBL4170461 0.81 GABRA1 (0.50) GABRA1GABRB2AKR1B1MEN1KMT2A
Ammonia Solution, Strong SCHEMBL2410475 0.81 GABRA1 (0.45) GABRA1GABRB2AKR1B1MEN1KMT2A
SCHEMBL10625097 0.79 GABRA1 (0.48) GABRA1GABRB2AKR1B1MEN1KMT2A
SCHEMBL1653593 0.79 GABRA1 (0.47) GABRA1GABRB2AKR1B1MEN1KMT2A
SCHEMBL31297411 0.79 GABRA1 (0.47) GABRA1GABRB2AKR1B1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9908959-B2 Polyacrylamide resin, papermaking additive, and paper HARIMA CHEMICALS, INCORPORATED (JP) 2018-03-06 US disclosed
US-20170253683-A1 POLYACRYLAMIDE RESIN, PAPERMAKING ADDITIVE, AND PAPER HARIMA CHEMICALS, INCORPORATED (JP) 2017-09-07 US disclosed