SCHEMBL7705575

SCHEMBL7705575

C=CCc1ccc(CCl)c(CCl)c1CC=C

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.34
GABRB2 P47870 2/20 0.34
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1918099 0.84 GABRA1 (0.43) GABRA1GABRB2POLB
SCHEMBL28175466 0.83 GABRA1 (0.47) GABRA1GABRB2
Ammonia Solution, Strong SCHEMBL19307331 0.82 GABRA1 (0.46) GABRA1GABRB2
SCHEMBL28398132 0.78 GABRA1 (0.50) GABRA1GABRB2
SCHEMBL10904076 0.78 GABRA1 (0.39) GABRA1GABRB2POLB
SCHEMBL1045560 0.76 L3MBTL1 (0.36)
SCHEMBL4629842 0.75 PON1 (0.35)
SCHEMBL2672546 0.74 GABRA1 (0.36) GABRA1GABRB2POLB
SCHEMBL5831559 0.74 GABRA1 (0.36) GABRA1GABRB2POLB
SCHEMBL1119848 0.74 GABRA1 (0.36) GABRA1GABRB2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6355826-B1 HALOMETHYLATION AN AROMATIC ALDEHYDE COMPOUND AND SALT FORMATION THE GOODYEAR TIRE & RUBBER COMPANY 2002-03-12 US disclosed
EP-0903338-A2 Synthesis of stable nitrile oxide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1999-03-24 EP disclosed
EP-0714556-B1 LIGHT-EMITTING DIODE COMPRISING AN ACTIVE LAYER OF 2,5-SUBSTITUTED POLY(P-PHENYLENE VINYLENE) KONINKL PHILIPS ELECTRONICS NV (NL) 1999-01-20 EP disclosed
EP-0714556-A1 LIGHT-EMITTING DIODE COMPRISING AN ACTIVE LAYER OF 2,5-SUBSTITUTED POLY(P-PHENYLENE VINYLENE) Koninklijke Philips Electronics N.V. (NL) 1996-06-05 EP disclosed
WO-1995032526-A1 LIGHT-EMITTING DIODE COMPRISING AN ACTIVE LAYER OF 2,5-SUBSTITUTED POLY(P-PHENYLENE VINYLENE) PHILIPS ELECTRONICS N.V. (NL) 1995-11-30 WO disclosed