SCHEMBL19307448

SCHEMBL19307448

CCC(C)Oc1ccc(F)c(-c2ccc(OCC3CC3C(=O)OC)cc2)c1

nearest known ligand 0.81

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 20/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19307450 1.00 FFAR4 (0.81) FFAR4
SCHEMBL19307446 1.00 FFAR4 (0.81) FFAR4
SCHEMBL20032787 0.90 FFAR4 (0.85) FFAR4
SCHEMBL19307411 0.90 FFAR4 (1.00) FFAR4
SCHEMBL17593098 0.90 FFAR4 (1.00) FFAR4
SCHEMBL19307410 0.90 FFAR4 (1.00) FFAR4
SCHEMBL19307447 0.85 FFAR4 (0.78) FFAR4
SCHEMBL19307445 0.85 FFAR4 (0.78) FFAR4
SCHEMBL19307402 0.84 FFAR4 (0.62) FFAR4
SCHEMBL19307413 0.84 FFAR4 (0.62) FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3191454-B1 CYCLOPROPANECARBOXYLIC ACID GPR120 MODULATORS BRISTOL MYERS SQUIBB CO (US) 2018-10-24 EP disclosed
US-9938222-B2 Cyclopropanecarboxylic acid GPR120 modulators BRISTOL-MYERS SQUIBB COMPANY (US) 2018-04-10 US disclosed
US-20170253554-A1 CYCLOPROPANECARBOXYLIC ACID GPR120 MODULATORS BRISTOL MYERS SQUIBB CO (US) 2017-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170253554-A1 CYCLOPROPANECARBOXYLIC ACID GPR120 MODULATORS GPR88, GPBAR1, GPR68 FFAR4 35/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.