SCHEMBL19307995

SCHEMBL19307995

Cc1cc(C(C)(c2ccc(O)c(-n3c(=O)c4cc5oc6cc7c(cc6oc5cc4c3=O)C3(C(C)C)c4ccccc4C7(C(C)C)c4cc5oc6cc7c(=O)n(C)c(=O)c7cc6oc5cc43)c2)C(F)(F)F)ccc1O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.33
HSP90AA1 P07900 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17678873 1.00 PGR (0.33) PGRHSP90AA1
SCHEMBL10007072 0.81 HSP90AA1 (0.40) PGRHSP90AA1
SCHEMBL17678869 0.77 KDM4E (0.34)
SCHEMBL17678874 0.75 NPSR1 (0.31)
SCHEMBL17678868 0.73
SCHEMBL17678871 0.72
SCHEMBL18053255 0.72
SCHEMBL10001435 0.71 HSP90AA1 (0.41) PGRHSP90AA1
SCHEMBL17678870 0.70
SCHEMBL17678872 0.69 SIRT2 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9751985-B2 Triptycene-based dianhydrides, polyimides, methods of making each, and methods of use KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2017-09-05 US disclosed