SCHEMBL10001435

SCHEMBL10001435

Cc1cc(C(c2ccc(O)c(-n3c(=O)c4cc5c(=O)n(C)c(=O)c5cc4c3=O)c2)(C(F)(F)F)C(F)(F)F)ccc1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 2/20 0.41
CYP2C9 P11712 2/20 0.41
MEN1 O00255 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPT P10636 1/20 0.41
TSHR P16473 1/20 0.41
NFKB1 P19838 1/20 0.41
CYP2C19 P33261 1/20 0.41
BLM P54132 1/20 0.41
PMP22 Q01453 1/20 0.41
KMT2A Q03164 1/20 0.41
KCNMA1 Q12791 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
KDM4E B2RXH2 1/20 0.40
POLB P06746 1/20 0.40
GAA P10253 1/20 0.40
AR P10275 4/20 0.38
PGR P06401 3/20 0.38
ESR1 P03372 11/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10007072 0.89 HSP90AA1 (0.40) HSP90AA1CYP2C9MEN1CYP1A2CYP3A4
SCHEMBL14163307 0.85 PGR (0.37) MEN1KMT2AKDM4EPOLBGAA
SCHEMBL29404885 0.76 ESR1 (0.59) ARESR1ESR2
SCHEMBL29925195 0.76 ESR1 (0.59) ARESR1ESR2
SCHEMBL3688722 0.76 ESR1 (0.59) ARESR1ESR2
SCHEMBL14163304 0.74 ESR1 (0.36) HSP90AA1CYP2C9MEN1CYP1A2CYP3A4
SCHEMBL12856287 0.74 PGR (0.39) MAPTTSHRKMT2AKDM4EPOLB
SCHEMBL9610064 0.73 TYMS (0.47) HSP90AA1MEN1KMT2AESR1NR1H3
SCHEMBL2622758 0.72 ESR1 (0.41) HSP90AA1CYP2C9MEN1CYP1A2CYP3A4
SCHEMBL16253392 0.71 ESR1 (0.53) ARESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200131314-A1 RESIN COMPOSITION, LAMINATE AND MANUFACTURING METHOD THEREOF, ELECTRODE, SECONDARY BATTERY, AND ELECTRIC DOUBLE LAYER CAPACITOR TORAY INDUSTRIES, INC. (JP) 2020-04-30 US disclosed
US-8501393-B2 Lithography; photoresists; semiconductors NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-08-06 US disclosed
US-20120160393-A1 METHOD FOR MAKING BISTABLE NEMATIC LIQUID-CRYSTAL DEVICES CDC PROPRIETE INTELLECTUELLE (FR) 2012-06-28 US disclosed
US-20080138744-A1 Anti-Reflective Coating Forming Composition Containing Vinyl Ether Compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2008-06-12 US disclosed