SCHEMBL19307996

SCHEMBL19307996

O=C(O)CCCCCCCCCCCCCCCCC(=O)NCCCC(=O)N[C@@H](CCC(=O)NCC(=O)O)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ NOD1 Q9Y239 4/20 0.55
▸ EPHX2 P34913 1/20 0.51
▸ GLP1R P43220 8/20 0.49
▸ GLO1 Q04760 1/20 0.48
▸ PTPN1 P18031 1/20 0.47
▸ FAAH O00519 1/20 0.46
▸ FOLH1 Q04609 1/20 0.46
▸ KDM4E B2RXH2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19308032 1.00 NOD1 (0.55) NOD1EPHX2GLP1RGLO1PTPN1
SCHEMBL21242900 0.94 NOD1 (0.59) NOD1EPHX2GLP1RGLO1PTPN1
SCHEMBL21242674 0.94 NOD1 (0.59) NOD1EPHX2GLP1RGLO1PTPN1
SCHEMBL14167624 0.94 NOD1 (0.59) NOD1EPHX2GLP1RGLO1PTPN1
SCHEMBL19776963 0.94 NOD1 (0.59) NOD1EPHX2GLP1RGLO1PTPN1
SCHEMBL24178469 0.94 NOD1 (0.59) NOD1EPHX2GLP1RGLO1PTPN1
SCHEMBL16273259 0.91 NOD1 (0.59) NOD1EPHX2GLP1RFOLH1
SCHEMBL19308060 0.91 NOD1 (0.52) NOD1EPHX2GLP1RFOLH1KDM4E
SCHEMBL19307981 0.89 NOD1 (0.55) NOD1EPHX2GLP1RFOLH1
SCHEMBL20215729 0.89 NOD1 (0.55) NOD1EPHX2GLP1RFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180044394-A1 STABLE, PROTRACTED GLP-1/GLUCAGON RECEPTOR CO-AGONISTS FOR MEDICAL USE NOVO NORDISK AS (DK) 2018-02-15 — — US disclosed
US-9751927-B2 Stable, protracted GLP-1/glucagon receptor co-agonists for medical use NOVO NORDISK A/S (DK) 2017-09-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180044394-A1 STABLE, PROTRACTED GLP-1/GLUCAGON RECEPTOR CO-AGONISTS FOR MEDICAL USE GLP1R, GIPR, GCGR NOD1 1398/4885EPHX2 4147/4885GLP1R 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback