Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | GLP1R | P43220 | 8/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.46 |
| ▸ | TYMS | P04818 | 1/20 | 0.44 |
| ▸ | GART | P22102 | 1/20 | 0.44 |
| ▸ | ATIC | P31939 | 1/20 | 0.44 |
| ▸ | GNPAT | O15228 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19307981 | 1.00 | NOD1 (0.55) | NOD1EPHX2GLP1RFOLH1TYMS | |
| SCHEMBL16273259 | 0.91 | NOD1 (0.59) | NOD1EPHX2GLP1RFOLH1TYMS | |
| SCHEMBL14167460 | 0.91 | NOD1 (0.62) | NOD1EPHX2FOLH1GNPAT | |
| SCHEMBL18735827 | 0.91 | NOD1 (0.62) | NOD1EPHX2FOLH1GNPAT | |
| SCHEMBL19307982 | 0.90 | NOD1 (0.54) | NOD1EPHX2GLP1RFOLH1 | |
| SCHEMBL19786616 | 0.89 | NOD1 (0.69) | NOD1EPHX2GLP1R | |
| SCHEMBL20215725 | 0.89 | NOD1 (0.69) | NOD1EPHX2GLP1R | |
| SCHEMBL19307996 | 0.89 | NOD1 (0.55) | NOD1EPHX2GLP1RFOLH1 | |
| SCHEMBL19308032 | 0.89 | NOD1 (0.55) | NOD1EPHX2GLP1RFOLH1 | |
| SCHEMBL20215727 | 0.89 | NOD1 (0.69) | NOD1EPHX2GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9988430-B2 | Stable GLP-1 based GLP-1/glucagon receptor co-agonists | NOVO NORDISK A/S (DK) | 2018-06-05 | — | — | US | disclosed |