SCHEMBL19308014

CC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)CC[C@H](NC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCCCCCC(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	NMT1	P30419	6/20	0.49

▸	NMT2	O60551	5/20	0.49

▸	NOD1	Q9Y239	3/20	0.49

▸	GLP1R	P43220	8/20	0.44

▸	GLO1	Q04760	1/20	0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL19867245	1.00	NMT1 (0.49)	NMT1NMT2NOD1GLP1RGLO1
SCHEMBL17375884	0.98	NMT1 (0.47)	NMT1NMT2NOD1GLP1RGLO1
SCHEMBL21100058	0.98	NMT1 (0.47)	NMT1NMT2NOD1GLP1RGLO1
SCHEMBL19308062	0.97	NOD1 (0.51)	NMT1NMT2NOD1GLP1R
SCHEMBL17682348	0.96	NOD1 (0.52)	NMT1NMT2NOD1GLP1RGLO1
SCHEMBL16156108	0.95	NOD1 (0.49)	NMT1NMT2NOD1GLP1RGLO1
SCHEMBL16156102	0.95	NOD1 (0.49)	NMT1NMT2NOD1GLP1RGLO1
SCHEMBL21099794	0.93	NMT1 (0.44)	NMT1NMT2NOD1GLP1RGLO1
SCHEMBL21418066	0.91	NOD1 (0.47)	NMT1NMT2NOD1GLP1RGLO1
SCHEMBL20375263	0.91	NOD1 (0.47)	NMT1NMT2NOD1GLP1RGLO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-9751927-B2	Stable, protracted GLP-1/glucagon receptor co-agonists for medical use	NOVO NORDISK A/S (DK)	2017-09-05	—	—	US	disclosed