Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.47 |
| ▸ | GLP1R | P43220 | 8/20 | 0.43 |
| ▸ | NMT2 | O60551 | 1/20 | 0.43 |
| ▸ | NMT1 | P30419 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21418066 | 1.00 | NOD1 (0.47) | NOD1GLP1RNMT2NMT1GLO1 | |
| SCHEMBL16156108 | 0.95 | NOD1 (0.49) | NOD1GLP1RNMT2NMT1GLO1 | |
| SCHEMBL16156102 | 0.95 | NOD1 (0.49) | NOD1GLP1RNMT2NMT1GLO1 | |
| SCHEMBL17682348 | 0.94 | NOD1 (0.52) | NOD1GLP1RNMT2NMT1GLO1 | |
| SCHEMBL21100058 | 0.93 | NMT1 (0.47) | NOD1GLP1RNMT2NMT1GLO1 | |
| SCHEMBL17375884 | 0.93 | NMT1 (0.47) | NOD1GLP1RNMT2NMT1GLO1 | |
| SCHEMBL16712658 | 0.92 | NOD1 (0.39) | NOD1GLP1RNMT2NMT1GLO1 | |
| SCHEMBL23964037 | 0.91 | TLR2 (0.45) | NOD1NMT2NMT1GLO1PTGS1 | |
| SCHEMBL19867245 | 0.91 | NMT1 (0.49) | NOD1GLP1RNMT2NMT1GLO1 | |
| SCHEMBL19308014 | 0.91 | NMT1 (0.49) | NOD1GLP1RNMT2NMT1GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214220-A1 | GLUCAGON ANALOGUES AS LONG-ACTING GLP-1/GLUCAGON RECEPTOR AGONISTS IN THE TREATMENT OF FATTY LIVER DISEASE AND STEATOHEPATITIS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-10-28 | — | — | WO | disclosed |
| EP-3065767-B1 | GIP-GLP-1 DUAL AGONIST COMPOUNDS AND METHODS | ZEALAND PHARMA AS (DK) | 2020-12-30 | — | — | EP | disclosed |
| EP-3057984-B1 | ACYLATED GLUCAGON ANALOGUES | ZEALAND PHARMA AS (DK) | 2018-07-11 | — | — | EP | disclosed |