Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 8/20 | 0.31 |
| ▸ | PTPRC | P08575 | 2/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19297705 | 0.88 | TTR (0.36) | ALDH1A1TTRBRD4PTPRCCTSL | |
| SCHEMBL19297706 | 0.88 | TTR (0.36) | ALDH1A1TTRBRD4PTPRCCTSL | |
| SCHEMBL19297707 | 0.88 | TTR (0.36) | ALDH1A1TTRBRD4PTPRCCTSL | |
| SCHEMBL19308145 | 0.83 | BRD4 (0.35) | ALDH1A1BRD4 | |
| SCHEMBL21998588 | 0.82 | ALDH1A1 (0.34) | TNKS2ALDH1A1PTPRCCTSLCTSS | |
| SCHEMBL19309487 | 0.81 | TNKS2 (0.37) | TNKS2 | |
| SCHEMBL19308146 | 0.78 | CYP1B1 (0.38) | ALDH1A1BRD4 | |
| SCHEMBL19297691 | 0.78 | ALDH1A1 (0.37) | ALDH1A1BRD4 | |
| SCHEMBL19297692 | 0.78 | ALDH1A1 (0.37) | ALDH1A1BRD4 | |
| SCHEMBL19297690 | 0.78 | ALDH1A1 (0.37) | ALDH1A1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9751896-B1 | Asymmetric 7-N isatin dimer Schiff base compounds with antitumor activities and a method of preparing the same | SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2017-09-05 | — | — | US | disclosed |
| US-9751896-B1 | Asymmetric 7-N isatin dimer Schiff base compounds with antitumor activities and a method of preparing the same | SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2017-09-05 | — | — | US | disclosed |