Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19309407 | 0.86 | KDM4E (0.33) | TNKS2KDM4EHKDC1 | |
| SCHEMBL19308152 | 0.81 | TNKS2 (0.33) | TNKS2 | |
| SCHEMBL19308145 | 0.75 | BRD4 (0.35) | KDM4EPKMSMN1; SMN2 | |
| SCHEMBL19297707 | 0.75 | TTR (0.36) | RAB9A | |
| SCHEMBL19297705 | 0.75 | TTR (0.36) | RAB9A | |
| SCHEMBL19297706 | 0.75 | TTR (0.36) | RAB9A | |
| SCHEMBL21998588 | 0.74 | ALDH1A1 (0.34) | TNKS2KDM4EPKM | |
| SCHEMBL19297691 | 0.70 | ALDH1A1 (0.37) | KDM4EPKMSMN1; SMN2 | |
| SCHEMBL19297692 | 0.70 | ALDH1A1 (0.37) | KDM4EPKMSMN1; SMN2 | |
| SCHEMBL19297690 | 0.70 | ALDH1A1 (0.37) | KDM4EPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9751896-B1 | Asymmetric 7-N isatin dimer Schiff base compounds with antitumor activities and a method of preparing the same | SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2017-09-05 | — | — | US | disclosed |