Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 3/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | MLNR | O43193 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3212630 | 0.91 | PKM (0.55) | PKMSLC6A2SLC6A4TSHRKCNH2 | |
| SCHEMBL5275182 | 0.86 | TSHR (0.59) | PKMSLC6A2SLC6A4TSHRMCOLN3 | |
| SCHEMBL10795379 | 0.77 | SLC6A2 (0.52) | PKMSLC6A2SLC6A4TSHRKCNH2 | |
| Hydrochloric Acid SCHEMBL10795422 | 0.76 | SLC6A2 (0.51) | PKMSLC6A2SLC6A4TSHRKCNH2 | |
| SCHEMBL19308229 | 0.76 | F2 (0.52) | PKMTSHRMCOLN3LMNAALDH1A1 | |
| SCHEMBL12929587 | 0.75 | PKM (0.54) | PKMSLC6A2SLC6A4TSHRKCNH2 | |
| SCHEMBL19308198 | 0.73 | TSHR (0.47) | TSHRKCNH2MCOLN3LMNAALDH1A1 | |
| SCHEMBL933358 | 0.72 | KMT2A (0.61) | PKMSLC6A2SLC6A4KCNH2SLC6A3 | |
| SCHEMBL932265 | 0.72 | NPY5R (0.66) | SLC6A2SLC6A4KCNH2SLC6A3HTR6 | |
| Hydrochloric Acid SCHEMBL6793584 | 0.71 | KMT2A (0.60) | PKMSLC6A2SLC6A4KCNH2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9752149-B2 | Matriptase inhibitors and uses thereof against orthomyxoviridae infections | SOCPRA Sciences Sante et Humaines S.E.C. (CA) | 2017-09-05 | — | — | US | disclosed |