Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.52 |
| ▸ | F10 | P00742 | 2/20 | 0.52 |
| ▸ | PLG | P00747 | 2/20 | 0.52 |
| ▸ | PLAU | P00749 | 2/20 | 0.52 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.52 |
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | MC5R | P33032 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12929584 | 0.81 | F2 (0.52) | F2F10PLGPLAUST14 | |
| SCHEMBL19308228 | 0.79 | MC4R (0.47) | F2F10PLGPLAUST14 | |
| SCHEMBL19308224 | 0.79 | F2 (0.49) | F2F10PLGPLAUST14 | |
| SCHEMBL5275182 | 0.79 | TSHR (0.59) | F2MCOLN3LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8546806 | 0.77 | AKR1C3 (0.51) | MCOLN3LMNAALDH1A1KDM4EHTT | |
| SCHEMBL19308227 | 0.76 | PKM (0.54) | MCOLN3LMNAALDH1A1AKR1C3AKR1C1 | |
| SCHEMBL19308204 | 0.75 | ALDH1A1 (0.51) | F2F10LMNAALDH1A1HTT | |
| SCHEMBL19308200 | 0.72 | F2 (0.43) | F2F10PLGPLAUST14 | |
| SCHEMBL6793156 | 0.71 | GPR119 (0.50) | LMNAALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL19308197 | 0.70 | HDAC3 (0.46) | F2F10LMNAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9752149-B2 | Matriptase inhibitors and uses thereof against orthomyxoviridae infections | SOCPRA Sciences Sante et Humaines S.E.C. (CA) | 2017-09-05 | — | — | US | disclosed |