Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 12/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16704191 | 0.84 | HPGD (0.56) | CMA1LMNAHPGDSMN1; SMN2MAPT | |
| SCHEMBL14580058 | 0.81 | ATM (0.45) | CMA1LMNAHPGDSMN1; SMN2MAPT | |
| SCHEMBL31347244 | 0.81 | ATM (0.45) | CMA1LMNAHPGDSMN1; SMN2MAPT | |
| SCHEMBL30884547 | 0.81 | LMNA (0.60) | CMA1HTTLMNASMN1; SMN2MAPT | |
| SCHEMBL29208209 | 0.81 | LMNA (0.60) | CMA1HTTLMNASMN1; SMN2MAPT | |
| SCHEMBL9776285 | 0.80 | MAPT (0.50) | CMA1HTTLMNAMAPTALDH1A1 | |
| SCHEMBL19308392 | 0.79 | CCNC (0.41) | CMA1MAPTALDH1A1 | |
| SCHEMBL8919351 | 0.78 | MAPT (0.49) | CMA1HTTLMNASMN1; SMN2MAPT | |
| SCHEMBL9776304 | 0.78 | KAT2B (0.49) | CMA1SMN1; SMN2MAPTALDH1A1MAPK1 | |
| SCHEMBL11259287 | 0.78 | SIRT6 (0.56) | HTTLMNAHPGDSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9751843-B2 | Substituted uracils and use thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-05 | — | — | US | disclosed |