Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 3/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.33 |
| ▸ | SLC47A1 | Q96FL8 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | STAT6 | P42226 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL811709 | 0.76 | GRIN2D (0.36) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Ammonia Solution, Strong SCHEMBL3787685 | 0.74 | GRIN2D (0.35) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Water SCHEMBL27943536 | 0.74 | GRIN2D (0.35) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Bromide SCHEMBL28280728 | 0.74 | GRIN2D (0.35) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8775129 | 0.72 | GRIN2D (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Iodide SCHEMBL529148 | 0.72 | GRIN2D (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Fluoride SCHEMBL29040384 | 0.72 | GRIN2D (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL1200522 | 0.72 | LMNA (0.43) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL20526370 | 0.72 | GRIN2D (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Ammonia Solution, Strong SCHEMBL528152 | 0.72 | GRIN2D (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1267403-C | Namenda synthesis method | BEIJING ACADEMY OF MILITARY ME (CN) | 2006-08-02 | — | — | CN | claimed |
| CN-1544415-A | Namenda synthesis method | 中国人民解放军北京军医学院 | 2004-11-10 | — | — | CN | claimed |
| EP-2091999-B1 | NOVEL NANOPARTICLE CONTAINING SILOXANE POLYMERS | PIBOND OY (FI) | 2020-08-12 | — | — | EP | disclosed |
| EP-1891145-B1 | METHOD FOR PRODUCING A POLYMER FOR SEMICONDUCTOR OPTOELECTRONICS COMPRISING POLYMERIZING FUNCTIONALIZED SILANE MONOMERS WITH BRIDGING HYDROCARBON GROUP | PIBOND OY (FI) | 2017-08-09 | — | — | EP | disclosed |
| EP-1891146-B1 | ORGANO FUNCTIONALIZED SILANE MONOMERS AND SILOXANE POLYMERS OF THE SAME | SILECS OY (FI) | 2015-01-14 | — | — | EP | disclosed |
| US-20140217539-A1 | SEMICONDUCTOR OPTOELECTRONICS DEVICES | SILECS OY (FI) | 2014-08-07 | — | — | US | disclosed |
| US-20130193543-A1 | SEMICONDUCTOR OPTOELECTRONICS DEVICES | SILECS OY (FI) | 2013-08-01 | — | — | US | disclosed |
| CN-102942490-A | Synthesis of memantine hydrochloride | SHAANXI ARK PHARMACEUTICAL CO LTD | 2013-02-27 | — | — | CN | disclosed |
| US-7955660-B2 | Silane monomers and siloxane polymers for semiconductor optoelectronics | SILECS OY (FI) | 2011-06-07 | — | — | US | disclosed |
| US-7833820-B2 | Nanoparticle containing siloxane polymers | SILECS OY (FI) | 2010-11-16 | — | — | US | disclosed |
| US-20100137448-A1 | Methods for Treating Neuropsychiatric Disorders with NMDA Receptor Antagonists | NEUROMOLECULAR, INC. | 2010-06-03 | — | — | US | disclosed |
| US-6620845-B2 | For therapy and prophylaxis of neurological diseases | NEUROMOLECULAR, INC. | 2003-09-16 | — | — | US | disclosed |
| US-20030008889-A1 | Aminoadamantane derivatives as therapeutic agents | PANORAMA RESEARCH, INC. | 2003-01-09 | — | — | US | disclosed |
| EP-1259477-A1 | AMINOADAMANTANE DERIVATIVES AS THERAPEUTIC AGENTS | PANORAMA RESEARCH, INC. (US) | 2002-11-27 | — | — | EP | disclosed |
| US-6444702-B1 | CENTRAL NERVOUS SYSTEM DISORDERS | NEUROMOLECULAR, INC. | 2002-09-03 | — | — | US | disclosed |
| WO-2001062706-A1 | AMINOADAMANTANE DERIVATIVES AS THERAPEUTIC AGENTS | PANORAMA RESEARCH, INC. (US) | 2001-08-30 | — | — | WO | disclosed |
| EP-0053621-B1 | UNSATURATED ESTERS OF ADAMANTANE CONTAINING DIOLS AND THERMO-RESISTANT CROSS-LINKED POLYMERS THEREFROM | BATTELLE MEMORIAL INSTITUTE (CH) | 1984-07-25 | — | — | EP | disclosed |
| EP-0053621-A1 | UNSATURATED ESTERS OF ADAMANTANE CONTAINING DIOLS AND THERMO-RESISTANT CROSS-LINKED POLYMERS THEREFROM. | BATTELLE MEMORIAL INSTITUTE (CH) | 1982-06-16 | — | — | EP | disclosed |
| US-4332964-A | Unsaturated esters of adamantane containing diols and thermo-resistant cross-linked polymers therefrom | BATTELLE DEVELOPMENT CORPORATION (US) | 1982-06-01 | — | — | US | disclosed |
| WO-1981003657-A1 | UNSATURATED ESTERS OF ADAMANTANE CONTAINING DIOLS AND THERMO-RESISTANT CROSS-LINKED POLYMERS THEREFROM | BATTELLE MEMORIAL INSTITUTE (CH) | 1981-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137448-A1 | Methods for Treating Neuropsychiatric Disorders with NMDA Receptor Antagonists | GRIN2A, GRIN1, GRIN3A | GRIN2D 8/4885GRIN3B 9/4885GRIN1 2/4885 |
| US-20030008889-A1 | Aminoadamantane derivatives as therapeutic agents | CHRNA4, CHRNA10, BACE1 | GRIN2D 163/4885GRIN3B 251/4885GRIN1 287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.