Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Ammonia Solution, Strong. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2A known ✓ | Q12879 | 3/20 | 0.33 |
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.32 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.32 |
| ▸ | SLC47A1 | Q96FL8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | STAT6 | P42226 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL28310363 | 1.00 | GRIN2D (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Ammonia Solution, Strong SCHEMBL28310364 | 1.00 | GRIN2D (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Water SCHEMBL27943536 | 0.97 | GRIN2D (0.35) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Ammonia Solution, Strong SCHEMBL3787685 | 0.97 | GRIN2D (0.35) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL28274675 | 0.95 | LMNA (0.36) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Bromide SCHEMBL28326375 | 0.95 | GRIN2D (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Fluoride SCHEMBL29040384 | 0.95 | GRIN2D (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Iodide SCHEMBL529148 | 0.95 | GRIN2D (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL811709 | 0.95 | GRIN2D (0.36) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Bromide SCHEMBL28280728 | 0.92 | GRIN2D (0.35) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 361 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118026963-A | Method for producing epoxide by olefin epoxidation | 中国石油化工股份有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-118026196-A | Synthetic method of pure silicon CHA molecular sieve | 南京工业大学 | 2024-05-14 | — | — | CN | claimed |
| CN-117959939-A | W-SSZ-13 molecular sieve membrane, preparation method thereof and application thereof in gas separation | 南京工业大学 | 2024-05-03 | — | — | CN | claimed |
| US-11925928-B2 | Self-cleaning fabric and article | CITY UNIVERSITY OF HONG KONG (HK) | 2024-03-12 | — | — | US | claimed |
| CN-116375050-B | SSZ-13 molecular sieve with high silicon-aluminum ratio, preparation method thereof, acoustic reinforcing material, loudspeaker and electronic equipment | 镇江贝斯特新材料股份有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-114835136-B | Hierarchical pore beta molecular sieve with ordered mesoporous structure, preparation method and application | 天津大学 | 2023-12-26 | — | — | CN | claimed |
| CN-116002709-B | Preparation method of SSZ-13 molecular sieve membrane | 南京工业大学 | 2023-12-22 | — | — | CN | claimed |
| CN-117258833-A | Tightly-coupled SCR post-treatment composite catalyst and preparation method and application thereof | 中国石油大学(北京) | 2023-12-22 | — | — | CN | claimed |
| US-20230405572-A1 | SELF-CLEANING FABRIC AND ARTICLE | CITY UNIVERSITY OF HONG KONG (HK) | 2023-12-21 | — | — | US | claimed |
| CN-114835133-B | Preparation method of SSZ-13 molecular sieve with multistage pore structure, obtained product and application | 济南大学 | 2023-08-11 | — | — | CN | claimed |
| CN-108212538-A | A kind of alkyl thioether group alcohol compound and preparation method and application | 中南大学 | 2018-06-29 | — | — | CN | claimed |
| CN-107758691-A | The preparation method of the high molecular sieves of silicon CHA types SSZ 13 | 太原理工大学 | 2018-03-06 | — | — | CN | claimed |
| CN-106082261-B | A kind of Ti MWW molecular sieves and preparation method thereof | 中触媒新材料股份有限公司 | 2018-03-02 | — | — | CN | claimed |
| CN-107497482-A | A kind of preparation and application of new type low temperature composite catalyst | 廊坊市北辰创业树脂材料有限公司 | 2017-12-22 | — | — | CN | claimed |
| CN-106629761-B | A kind of synthetic method of the molecular sieves of SSZ 13 | 上海卓悦化工科技有限公司 | 2017-11-24 | — | — | CN | claimed |
| CN-104190464-B | A kind of Sn bases micro porous molecular sieve NOx SCR catalyst preparation methods | 南昌大学 | 2017-11-03 | — | — | CN | claimed |
| CN-107282096-A | A kind of SSZ-13 molecular sieve catalysts and preparation method and application | 中触媒新材料股份有限公司 | 2017-10-24 | — | — | CN | claimed |
| CN-106622356-A | Copper modified molecular sieve selective reduction catalyst, preparation method and applications thereof | 中触媒新材料股份有限公司 | 2017-05-10 | — | — | CN | claimed |
| CN-106587097-A | Method for synthesizing SSZ-13 zeolite molecular sieve by utilizing micron-silicon powder | 中国地质大学（武汉） | 2017-04-26 | — | — | CN | claimed |
| CN-106391104-A | Preparation of a metal manganese modified silicon-aluminum molecular sieve material Mn-SSZ-13, and applications of the material in alkene preparation from methanol and denitration | 天津工业大学 | 2017-02-15 | — | — | CN | claimed |