Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3723514 | 0.85 | — | — | |
| SCHEMBL27855544 | 0.80 | FDPS (0.39) | FDPSCYP2D6KCNE1KCNA5 | |
| SCHEMBL1285192 | 0.77 | — | — | |
| SCHEMBL3650252 | 0.76 | HTT (0.35) | — | |
| SCHEMBL8834121 | 0.73 | FDPS (0.33) | FDPSCYP2D6KCNE1KCNA5 | |
| SCHEMBL20225634 | 0.73 | FDPS (0.33) | FDPSCYP2D6KCNE1KCNA5 | |
| SCHEMBL3698990 | 0.69 | — | — | |
| SCHEMBL975264 | 0.69 | FDPS (0.42) | FDPSKCNA5 | |
| SCHEMBL15133972 | 0.68 | FDPS (0.38) | FDPSCYP2D6KCNE1KCNA5 | |
| SCHEMBL7775089 | 0.68 | FDPS (0.38) | FDPSCYP2D6KCNE1KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300013-B1 | PHOSPHOROUS DERIVATIVES AS KINASE INHIBITORS | ARIAD PHARMA INC (US) | 2017-09-06 | — | — | EP | disclosed |