Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 13/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL30330453 | 0.95 | ALOX5 (0.36) | ALOX5CCR5 | |
| Hydrochloric Acid SCHEMBL30330243 | 0.95 | ALOX5 (0.36) | ALOX5CCR5 | |
| Hydrochloric Acid SCHEMBL30329955 | 0.95 | ALOX5 (0.36) | ALOX5CCR5 | |
| Fluoride SCHEMBL30330085 | 0.95 | ALOX5 (0.36) | ALOX5CCR5 | |
| Fluoride SCHEMBL30329870 | 0.95 | ALOX5 (0.36) | ALOX5CCR5 | |
| Fluoride SCHEMBL30329848 | 0.95 | ALOX5 (0.36) | ALOX5CCR5 | |
| Fluoride SCHEMBL30329926 | 0.93 | ALOX5 (0.34) | ALOX5CCR5MGLLFAAH | |
| Hydrochloric Acid SCHEMBL30329985 | 0.90 | CCR5 (0.36) | ALOX5CCR5 | |
| Hydrochloric Acid SCHEMBL30329893 | 0.90 | CCR5 (0.36) | ALOX5CCR5 | |
| SCHEMBL14818807 | 0.90 | CCR5 (0.39) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3024833-B1 | NOVEL INDOLIZINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2017-09-06 | — | — | EP | disclosed |