SCHEMBL19320195

SCHEMBL19320195

Brc1ccc(-c2ccc(-c3nc(-c4ccccc4)c4ccccc4n3)cc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.69
KMT2A Q03164 2/20 0.69
ATM Q13315 1/20 0.69
CYP1B1 Q16678 3/20 0.62
CYP1A1 P04798 1/20 0.62
CYP1A2 P05177 1/20 0.62
ABCG2 Q9UNQ0 5/20 0.57
NUDT1 P36639 3/20 0.50
ALDH1A1 P00352 1/20 0.50
MAPK1 P28482 1/20 0.50
NPC1 O15118 1/20 0.50
NFKB1 P19838 1/20 0.50
RAB9A P51151 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
ADORA2A P29274 1/20 0.50
TP53 P04637 1/20 0.49
WHR1 P49842 1/20 0.48
NR1H4 Q96RI1 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31683846 1.00 MEN1 (0.69) MEN1KMT2AATMCYP1B1CYP1A1
SCHEMBL23352770 1.00 MEN1 (0.69) MEN1KMT2AATMCYP1B1CYP1A1
SCHEMBL22603326 1.00 MEN1 (0.69) MEN1KMT2AATMCYP1B1CYP1A1
SCHEMBL15003695 1.00 MEN1 (0.69) MEN1KMT2AATMCYP1B1CYP1A1
SCHEMBL16211433 0.98 MEN1 (0.71) MEN1KMT2AATMCYP1B1CYP1A1
SCHEMBL29674917 0.98 MEN1 (0.71) MEN1KMT2AATMCYP1B1CYP1A1
SCHEMBL9889191 0.98 MEN1 (0.71) MEN1KMT2AATMCYP1B1CYP1A1
SCHEMBL18455708 0.97 MEN1 (0.68) MEN1KMT2AATMCYP1B1CYP1A1
SCHEMBL16231231 0.92 MEN1 (0.59) MEN1KMT2AATMCYP1B1CYP1A1
SCHEMBL22058673 0.91 MEN1 (0.80) MEN1KMT2AATMCYP1B1CYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170256719-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRICAL ELEMENT USING COMPOUND, AND ELECTRONIC DEVICE COMPRISING SAME DUK SAN NEOLUX CO., LTD (KR) 2017-09-07 US disclosed
US-20170256719-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRICAL ELEMENT USING COMPOUND, AND ELECTRONIC DEVICE COMPRISING SAME DUK SAN NEOLUX CO., LTD (KR) 2017-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170256719-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRICAL ELEMENT USING COMPOUND, AND ELECTRONIC DEVICE COMPRISING SAME ORAI2, VDAC2, PIEZO1 MEN1 1271/4885KMT2A 727/4885ATM 2903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.