Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620189 | 0.84 | ALDH1A1 (0.49) | MEN1KMT2AL3MBTL1TDP1CYP2C19 | |
| SCHEMBL8009306 | 0.82 | ALDH1A1 (0.47) | MEN1KMT2AL3MBTL1TDP1CYP2C19 | |
| SCHEMBL19320580 | 0.81 | ALDH1A1 (0.40) | MEN1KMT2AL3MBTL1TDP1CYP2C19 | |
| SCHEMBL599659 | 0.74 | CYP2C19 (0.62) | TDP1ACP3CYP3A4CYP2C19CTRC | |
| SCHEMBL29490353 | 0.74 | CYP2C19 (0.62) | TDP1ACP3CYP3A4CYP2C19CTRC | |
| SCHEMBL11328087 | 0.72 | CYP2C19 (0.60) | TDP1ACP3CYP3A4CYP2C19CTRC | |
| SCHEMBL659516 | 0.72 | CYP2C19 (0.60) | TDP1ACP3CYP3A4CYP2C19CTRC | |
| SCHEMBL659517 | 0.72 | CYP2C19 (0.60) | TDP1ACP3CYP3A4CYP2C19CTRC | |
| Hydrogen Sulfide SCHEMBL11348128 | 0.72 | CYP2C19 (0.60) | TDP1ACP3CYP3A4CYP2C19CTRC | |
| SCHEMBL11339937 | 0.72 | CYP2C19 (0.60) | TDP1ACP3CYP3A4CYP2C19CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170255103-A1 | PATTERN TRIMMING METHODS | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2017-09-07 | — | — | US | disclosed |
| US-20170255102-A1 | PATTERN TRIMMING COMPOSITIONS AND METHODS | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2017-09-07 | — | — | US | disclosed |