SCHEMBL8620189

SCHEMBL8620189

O=S(O)Oc1cccc2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.49
KDM4E B2RXH2 4/20 0.49
HPGD P15428 2/20 0.49
TDP1 Q9NUW8 1/20 0.49
HSD17B10 Q99714 3/20 0.47
GAA P10253 2/20 0.47
PGR P06401 1/20 0.47
PTGS1 P23219 1/20 0.47
MAPK1 P28482 1/20 0.47
KMT2A Q03164 4/20 0.46
MEN1 O00255 2/20 0.46
RAB9A P51151 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
OGG1 O15527 1/20 0.44
HTR1B P28222 2/20 0.43
CYP1A2 P05177 1/20 0.42
CYP2C19 P33261 1/20 0.42
TSHR P16473 1/20 0.41
POLB P06746 1/20 0.41
NR2E1 Q9Y466 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8009306 0.98 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL19320580 0.89 ALDH1A1 (0.40) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL19320581 0.84 MEN1 (0.43) ALDH1A1KDM4EHPGDTDP1KMT2A
SCHEMBL11076220 0.83 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL6759877 0.80 CA1 (0.35) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL13707230 0.78 ESR1 (0.49) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL15254631 0.78 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL19320583 0.76 KMT2A (0.41) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL13707229 0.74 IDO1 (0.50) HSD17B10GAAKMT2AMEN1
SCHEMBL19320585 0.74 PRMT1 (0.44) ALDH1A1KDM4EHPGDTDP1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5789054-A Spin-transition parent compounds and devices having means for writing, storing and erasing, which comprise an active medium including at least one of said compounds U.S. PHILIPS CORPORATION (US) 1998-08-04 US disclosed
EP-0842988-A1 Spin-transition chemical compounds and temperature threshold crossing display devices comprising an active medium which contains at least one of those compounds DE LA RUE CARTES ET SYSTEMES (FR) 1998-05-20 EP disclosed
EP-0745986-A1 Spin-transition chemical starting compounds and devices provided with writing, memorizing and erasing means comprising an active medium that contains at least one of these compounds LABORATOIRES D'ELECTRONIQUE PHILIPS S.A.S. (FR) 1996-12-04 EP disclosed