Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19320914 | 0.85 | PARP10 (0.44) | MEN1KMT2AATMNCEH1 | |
| SCHEMBL897607 | 0.84 | KDM4E (0.55) | KDM4EALDH1A1MEN1CYP1A2GLA | |
| SCHEMBL19320915 | 0.84 | KDM4E (0.43) | KDM4EALDH1A1MEN1GLAKMT2A | |
| SCHEMBL19325530 | 0.83 | KDM4E (0.50) | KDM4EALDH1A1MEN1CYP1A2GLA | |
| Ammonia Solution, Strong SCHEMBL7720474 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1MEN1CYP1A2GLA | |
| Ammonia Solution, Strong SCHEMBL7720478 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1MEN1CYP1A2GLA | |
| SCHEMBL29913819 | 0.82 | KDM4E (0.57) | KDM4EALDH1A1MEN1CYP1A2GLA | |
| SCHEMBL1696920 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1MEN1CYP1A2GLA | |
| SCHEMBL28145097 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1MEN1CYP1A2GLA | |
| SCHEMBL7798078 | 0.80 | KDM4E (0.58) | KDM4EALDH1A1GLAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170253607-A1 | LONG-ACTING HIV PROTEASE INHIBITOR | SHIONOGI & CO., LTD. (JP) | 2017-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170253607-A1 | LONG-ACTING HIV PROTEASE INHIBITOR | CPN1, HAT1, PRSS1 | KDM4E 1195/4885ALDH1A1 4195/4885MEN1 4668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.